Vibrometry: A novel noninvasive application of ultrasonographic physics to estimate wall stress in native aneurysms

Gautam Agarwal, Geza Mozes, Randall R. Kinnick, Peter Gloviczki, Russell E. Bruhnke, Michele Carmo, Tanya L. Hoskin, Kevin E. Bennett, James F Greenleaf

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Our objective was to test vibrometry as a means to measure changes in aneurysm sac pressure in an in vitro aneurysm model. Explanted porcine abdominal aortas and nitrile rubber tubes were used to model an aneurysm sac. An ultrasound beam was used to vibrate the surface of the aneurysm model. The motion generated on the surface was detected either by reflected laser light or by a second ultrasound probe. This was recorded at different aneurysm pressures. The phase of the propagating wave was measured to assess changes in velocity and to see if there was a correlation with aneurysm pressure. The cumulative phase shift detected by laser or Doppler correlated well with increasing hydrostatic pressure in both the rubber and the porcine aorta model. The square of the mean pressure correlated well with the cumulative phase shift when dynamic pressure was generated by a pump. However, the pulse pressure was poorly correlated with the cumulative phase shift. Noninvasive measurement of changes in aortic aneurysm sac tension is feasible in an in vitro setting using the concept of vibrometry. This could potentially be used to noninvasively detectwall stress in native aneurysms and endotension after endovascular aneurysm repair (EVAR) and to predict the risk of rupture.

Original languageEnglish (US)
Title of host publicationAnnals of the New York Academy of Sciences
Pages197-207
Number of pages11
Volume1085
DOIs
StatePublished - Nov 2006

Publication series

NameAnnals of the New York Academy of Sciences
Volume1085
ISSN (Print)00778923
ISSN (Electronic)17496632

Fingerprint

Physics
Aneurysm
Phase shift
Pressure
Rubber
Ultrasonics
Nitriles
Lasers
Swine
Hydrostatic pressure
Hydrostatic Pressure
Aortic Aneurysm
Abdominal Aorta
Repair
Pumps
Aorta
Rupture
Blood Pressure
Light

Keywords

  • Aneurysm
  • Ultrasound
  • Vibrometry

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Agarwal, G., Mozes, G., Kinnick, R. R., Gloviczki, P., Bruhnke, R. E., Carmo, M., ... Greenleaf, J. F. (2006). Vibrometry: A novel noninvasive application of ultrasonographic physics to estimate wall stress in native aneurysms. In Annals of the New York Academy of Sciences (Vol. 1085, pp. 197-207). (Annals of the New York Academy of Sciences; Vol. 1085). https://doi.org/10.1196/annals.1383.001

Vibrometry : A novel noninvasive application of ultrasonographic physics to estimate wall stress in native aneurysms. / Agarwal, Gautam; Mozes, Geza; Kinnick, Randall R.; Gloviczki, Peter; Bruhnke, Russell E.; Carmo, Michele; Hoskin, Tanya L.; Bennett, Kevin E.; Greenleaf, James F.

Annals of the New York Academy of Sciences. Vol. 1085 2006. p. 197-207 (Annals of the New York Academy of Sciences; Vol. 1085).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Agarwal, G, Mozes, G, Kinnick, RR, Gloviczki, P, Bruhnke, RE, Carmo, M, Hoskin, TL, Bennett, KE & Greenleaf, JF 2006, Vibrometry: A novel noninvasive application of ultrasonographic physics to estimate wall stress in native aneurysms. in Annals of the New York Academy of Sciences. vol. 1085, Annals of the New York Academy of Sciences, vol. 1085, pp. 197-207. https://doi.org/10.1196/annals.1383.001
Agarwal G, Mozes G, Kinnick RR, Gloviczki P, Bruhnke RE, Carmo M et al. Vibrometry: A novel noninvasive application of ultrasonographic physics to estimate wall stress in native aneurysms. In Annals of the New York Academy of Sciences. Vol. 1085. 2006. p. 197-207. (Annals of the New York Academy of Sciences). https://doi.org/10.1196/annals.1383.001
Agarwal, Gautam ; Mozes, Geza ; Kinnick, Randall R. ; Gloviczki, Peter ; Bruhnke, Russell E. ; Carmo, Michele ; Hoskin, Tanya L. ; Bennett, Kevin E. ; Greenleaf, James F. / Vibrometry : A novel noninvasive application of ultrasonographic physics to estimate wall stress in native aneurysms. Annals of the New York Academy of Sciences. Vol. 1085 2006. pp. 197-207 (Annals of the New York Academy of Sciences).
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