Vestibular testing abnormalities in individuals with motion sickness

Michael E. Hoffer, Kim Gottshall, Richard D. Kopke, Peter Weisskopf, Robert Moore, Keith A. Allen, Derin Wester

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Hypothesis: The goal of this study was to compare the results of vestibular testing in individuals with motion sickness to a group of control subjects. Background: Studying motion sickness is difficult, because no animal model has been developed and symptoms rarely occur outside motion environments. Tests that can be performed in normal laboratory settings, which help to identify individuals with motion sickness, may be valuable in characterizing this disorder. Methods: Twenty active duty military individuals with well-documented motion sickness were tested. The test battery included sinusoidal rotational chair testing to calculate vestibulo-ocular reflex function, step-velocity testing to calculate vestibular time constants, and posturography testing to assess vestibulo-spinal reflex status. The results of this test battery were compared with a set of age- and sex-matched controls without motion sickness. Results: Vestibular test abnormalities were demonstrated in individuals with motion sickness. Vestibulo-spinal reflex function on posturography was normal in the control group but abnormal in 70% of the individuals with motion sickness. In addition, 5% of the control group demonstrated a minimal shortening of the absolute time constant, whereas 60% of the individuals with motion sickness had abnormal absolute time constants. Conclusion: A significant percentage of individuals with motion sickness demonstrate abnormalities in their time constant or vestibulo-spinal reflex function. These abnormalities can be detected using standard, land-based vestibular tests. These preliminary results have implications in understanding the etiology of motion sickness and may provide outcome measures to be used in treating motion sickness.

Original languageEnglish (US)
Pages (from-to)633-636
Number of pages4
JournalOtology and Neurotology
Volume24
Issue number4
DOIs
StatePublished - Jan 1 2003
Externally publishedYes

Fingerprint

Motion Sickness
Reflex
Control Groups
Vestibulo-Ocular Reflex
Animal Models

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Sensory Systems
  • Clinical Neurology

Cite this

Hoffer, M. E., Gottshall, K., Kopke, R. D., Weisskopf, P., Moore, R., Allen, K. A., & Wester, D. (2003). Vestibular testing abnormalities in individuals with motion sickness. Otology and Neurotology, 24(4), 633-636. https://doi.org/10.1097/00129492-200307000-00017

Vestibular testing abnormalities in individuals with motion sickness. / Hoffer, Michael E.; Gottshall, Kim; Kopke, Richard D.; Weisskopf, Peter; Moore, Robert; Allen, Keith A.; Wester, Derin.

In: Otology and Neurotology, Vol. 24, No. 4, 01.01.2003, p. 633-636.

Research output: Contribution to journalArticle

Hoffer, ME, Gottshall, K, Kopke, RD, Weisskopf, P, Moore, R, Allen, KA & Wester, D 2003, 'Vestibular testing abnormalities in individuals with motion sickness', Otology and Neurotology, vol. 24, no. 4, pp. 633-636. https://doi.org/10.1097/00129492-200307000-00017
Hoffer, Michael E. ; Gottshall, Kim ; Kopke, Richard D. ; Weisskopf, Peter ; Moore, Robert ; Allen, Keith A. ; Wester, Derin. / Vestibular testing abnormalities in individuals with motion sickness. In: Otology and Neurotology. 2003 ; Vol. 24, No. 4. pp. 633-636.
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