Vestibular schwannoma management: Part II. Failed radiosurgery and the role of delayed microsurgery.

Bruce E. Pollock, L. Dade Lunsford, Douglas Kondziolka, Raymond Sekula, Brian R. Subach, Robert L. Foote, John C. Flickinger

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The indications, operative findings, and outcomes of vestibular schwannoma microsurgery are controversial when it is performed after stereotactic radiosurgery. To address these issues, the authors reviewed the experience at two academic medical centers. During a 10-year interval, 452 patients with unilateral vestibular schwannomas underwent gamma knife radiosurgery. Thirteen patients (2.9%) underwent delayed microsurgery at a median of 27 months (range 7-72 months) after they had undergone radiosurgery. Six of the 13 patients had undergone one or more microsurgical procedures before they underwent radiosurgery. The indications for surgery were tumor enlargement with stable symptoms in five patients, tumor enlargement with new or increased symptoms in five patients, and increased symptoms without evidence of tumor growth in three patients. Gross-total resection was achieved in seven patients and near-gross-total resection in four patients. The surgery was described as more difficult than that typically performed for schwannoma in eight patients, no different in four patients, and easier in one patient. At the last follow-up evaluation, three patients had normal or near-normal facial function, three patients had moderate facial dysfunction, and seven had facial palsies. Three patients were incapable of caring for themselves, and one patient died of progression of a malignant triton tumor. Failed radiosurgery in cases of vestibular schwannoma was rare. No clear relationship was demonstrated between the use of radiosurgery and the subsequent ease or difficulty of delayed microsurgery. Because some patients have temporary enlargement of their tumor after radiosurgery, the need for surgical resection after radiosurgery should be reviewed with the neurosurgeon who performed the radiosurgery and should be delayed until sustained tumor growth is confirmed. A subtotal tumor resection should be considered for patients who require surgical resection of their tumor after vestibular schwannoma radiosurgery.

Original languageEnglish (US)
Pages (from-to)949-955
Number of pages7
JournalJournal of Neurosurgery
Volume119 Suppl
StatePublished - 2013
Externally publishedYes

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Acoustic Neuroma
Microsurgery
Radiosurgery
Neoplasms
Facial Paralysis
Neurilemmoma
Growth

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Pollock, B. E., Lunsford, L. D., Kondziolka, D., Sekula, R., Subach, B. R., Foote, R. L., & Flickinger, J. C. (2013). Vestibular schwannoma management: Part II. Failed radiosurgery and the role of delayed microsurgery. Journal of Neurosurgery, 119 Suppl, 949-955.

Vestibular schwannoma management : Part II. Failed radiosurgery and the role of delayed microsurgery. / Pollock, Bruce E.; Lunsford, L. Dade; Kondziolka, Douglas; Sekula, Raymond; Subach, Brian R.; Foote, Robert L.; Flickinger, John C.

In: Journal of Neurosurgery, Vol. 119 Suppl, 2013, p. 949-955.

Research output: Contribution to journalArticle

Pollock, BE, Lunsford, LD, Kondziolka, D, Sekula, R, Subach, BR, Foote, RL & Flickinger, JC 2013, 'Vestibular schwannoma management: Part II. Failed radiosurgery and the role of delayed microsurgery.', Journal of Neurosurgery, vol. 119 Suppl, pp. 949-955.
Pollock BE, Lunsford LD, Kondziolka D, Sekula R, Subach BR, Foote RL et al. Vestibular schwannoma management: Part II. Failed radiosurgery and the role of delayed microsurgery. Journal of Neurosurgery. 2013;119 Suppl:949-955.
Pollock, Bruce E. ; Lunsford, L. Dade ; Kondziolka, Douglas ; Sekula, Raymond ; Subach, Brian R. ; Foote, Robert L. ; Flickinger, John C. / Vestibular schwannoma management : Part II. Failed radiosurgery and the role of delayed microsurgery. In: Journal of Neurosurgery. 2013 ; Vol. 119 Suppl. pp. 949-955.
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