Abstract
An elaborate vesicle transport system supports the active exchange of membranes and protein cargo between the plasma membrane and the trans-Golgi network. Many observations suggest that highly conserved mechanisms are used in vesicle formation and scission. Such similarity is found both at the level of the receptor-ligand sequestration process that uses clathrin and associated polymeric and monomeric adaptor proteins, and in the machinery used to deform and vesiculate lipid membranes.
Original language | English (US) |
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Pages (from-to) | 1591-1594 |
Number of pages | 4 |
Journal | Science |
Volume | 313 |
Issue number | 5793 |
DOIs | |
State | Published - Sep 15 2006 |
ASJC Scopus subject areas
- General