Vesicle formation at the plasma membrane and trans-Golgi network: The same but different

Mark A. McNiven; Heather M. Thompson

doi:10.1126/science.1118133

Vesicle formation at the plasma membrane and trans-Golgi network: The same but different

Mark A. McNiven, Heather M. Thompson

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

86 Scopus citations

Abstract

An elaborate vesicle transport system supports the active exchange of membranes and protein cargo between the plasma membrane and the trans-Golgi network. Many observations suggest that highly conserved mechanisms are used in vesicle formation and scission. Such similarity is found both at the level of the receptor-ligand sequestration process that uses clathrin and associated polymeric and monomeric adaptor proteins, and in the machinery used to deform and vesiculate lipid membranes.

Original language	English (US)
Pages (from-to)	1591-1594
Number of pages	4
Journal	Science
Volume	313
Issue number	5793
DOIs	https://doi.org/10.1126/science.1118133
State	Published - Sep 15 2006

ASJC Scopus subject areas

General

Access to Document

10.1126/science.1118133

Fingerprint Dive into the research topics of 'Vesicle formation at the plasma membrane and trans-Golgi network: The same but different'. Together they form a unique fingerprint.

Cite this

@article{e69a3c3728294923b037e425be8e69b5,

title = "Vesicle formation at the plasma membrane and trans-Golgi network: The same but different",

abstract = "An elaborate vesicle transport system supports the active exchange of membranes and protein cargo between the plasma membrane and the trans-Golgi network. Many observations suggest that highly conserved mechanisms are used in vesicle formation and scission. Such similarity is found both at the level of the receptor-ligand sequestration process that uses clathrin and associated polymeric and monomeric adaptor proteins, and in the machinery used to deform and vesiculate lipid membranes.",

author = "McNiven, {Mark A.} and Thompson, {Heather M.}",

year = "2006",

month = sep,

day = "15",

doi = "10.1126/science.1118133",

language = "English (US)",

volume = "313",

pages = "1591--1594",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "5793",

}

TY - JOUR

T1 - Vesicle formation at the plasma membrane and trans-Golgi network

T2 - The same but different

AU - McNiven, Mark A.

AU - Thompson, Heather M.

PY - 2006/9/15

Y1 - 2006/9/15

N2 - An elaborate vesicle transport system supports the active exchange of membranes and protein cargo between the plasma membrane and the trans-Golgi network. Many observations suggest that highly conserved mechanisms are used in vesicle formation and scission. Such similarity is found both at the level of the receptor-ligand sequestration process that uses clathrin and associated polymeric and monomeric adaptor proteins, and in the machinery used to deform and vesiculate lipid membranes.

AB - An elaborate vesicle transport system supports the active exchange of membranes and protein cargo between the plasma membrane and the trans-Golgi network. Many observations suggest that highly conserved mechanisms are used in vesicle formation and scission. Such similarity is found both at the level of the receptor-ligand sequestration process that uses clathrin and associated polymeric and monomeric adaptor proteins, and in the machinery used to deform and vesiculate lipid membranes.

UR - http://www.scopus.com/inward/record.url?scp=33748762242&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748762242&partnerID=8YFLogxK

U2 - 10.1126/science.1118133

DO - 10.1126/science.1118133

M3 - Review article

C2 - 16973870

AN - SCOPUS:33748762242

VL - 313

SP - 1591

EP - 1594

JO - Science

JF - Science

SN - 0036-8075

IS - 5793

ER -

Vesicle formation at the plasma membrane and trans-Golgi network: The same but different

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this