Vertebral osteomyelitis and prosthetic joint infection due to Staphylococcus simulans

Raymund R Razonable, D. G. Lewallen, Robin Patel, D. R. Osmon

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Staphylococcus simulans, a coagulase-negative staphylococcus, is a common animal pathogen that is rarely encountered in human infections. We describe a 70-year-old man who developed multifocal vertebral osteomyelitis and late prosthetic joint infection caused by this pathogen. The patient was a farmer who had daily contact with cows and drank unpasteurized milk, although the portal of the pathogen's entry remains speculative. Culture of the vertebral disk biopsy specimen and cultures during resection arthroplasty yielded S simulans. A review of the literature suggests that S simulans may be more virulent than other species of coagulase-negative staphylococci. Accurate identification of S simulans isolates would facilitate studies to further define its pathogenic role in human infections.

Original languageEnglish (US)
Pages (from-to)1067-1070
Number of pages4
JournalMayo Clinic Proceedings
Volume76
Issue number10
StatePublished - 2001

Fingerprint

Osteomyelitis
Staphylococcus
Joints
Coagulase
Infection
Arthroplasty
Milk
Biopsy

Keywords

  • CoNS = coagulase-negative staphylococcus
  • CRP = C-reactive protein
  • ESR = erythrocyte sedimentation rate
  • MRI = magnetic resonance imaging
  • PJI = prosthetic joint infection
  • THA = total hip arthroplasty
  • WBC = white blood cell

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vertebral osteomyelitis and prosthetic joint infection due to Staphylococcus simulans. / Razonable, Raymund R; Lewallen, D. G.; Patel, Robin; Osmon, D. R.

In: Mayo Clinic Proceedings, Vol. 76, No. 10, 2001, p. 1067-1070.

Research output: Contribution to journalArticle

@article{25a7d7e9eba74a268b8bb58384d4fd45,
title = "Vertebral osteomyelitis and prosthetic joint infection due to Staphylococcus simulans",
abstract = "Staphylococcus simulans, a coagulase-negative staphylococcus, is a common animal pathogen that is rarely encountered in human infections. We describe a 70-year-old man who developed multifocal vertebral osteomyelitis and late prosthetic joint infection caused by this pathogen. The patient was a farmer who had daily contact with cows and drank unpasteurized milk, although the portal of the pathogen's entry remains speculative. Culture of the vertebral disk biopsy specimen and cultures during resection arthroplasty yielded S simulans. A review of the literature suggests that S simulans may be more virulent than other species of coagulase-negative staphylococci. Accurate identification of S simulans isolates would facilitate studies to further define its pathogenic role in human infections.",
keywords = "CoNS = coagulase-negative staphylococcus, CRP = C-reactive protein, ESR = erythrocyte sedimentation rate, MRI = magnetic resonance imaging, PJI = prosthetic joint infection, THA = total hip arthroplasty, WBC = white blood cell",
author = "Razonable, {Raymund R} and Lewallen, {D. G.} and Robin Patel and Osmon, {D. R.}",
year = "2001",
language = "English (US)",
volume = "76",
pages = "1067--1070",
journal = "Mayo Clinic Proceedings",
issn = "0025-6196",
publisher = "Elsevier Science",
number = "10",

}

TY - JOUR

T1 - Vertebral osteomyelitis and prosthetic joint infection due to Staphylococcus simulans

AU - Razonable, Raymund R

AU - Lewallen, D. G.

AU - Patel, Robin

AU - Osmon, D. R.

PY - 2001

Y1 - 2001

N2 - Staphylococcus simulans, a coagulase-negative staphylococcus, is a common animal pathogen that is rarely encountered in human infections. We describe a 70-year-old man who developed multifocal vertebral osteomyelitis and late prosthetic joint infection caused by this pathogen. The patient was a farmer who had daily contact with cows and drank unpasteurized milk, although the portal of the pathogen's entry remains speculative. Culture of the vertebral disk biopsy specimen and cultures during resection arthroplasty yielded S simulans. A review of the literature suggests that S simulans may be more virulent than other species of coagulase-negative staphylococci. Accurate identification of S simulans isolates would facilitate studies to further define its pathogenic role in human infections.

AB - Staphylococcus simulans, a coagulase-negative staphylococcus, is a common animal pathogen that is rarely encountered in human infections. We describe a 70-year-old man who developed multifocal vertebral osteomyelitis and late prosthetic joint infection caused by this pathogen. The patient was a farmer who had daily contact with cows and drank unpasteurized milk, although the portal of the pathogen's entry remains speculative. Culture of the vertebral disk biopsy specimen and cultures during resection arthroplasty yielded S simulans. A review of the literature suggests that S simulans may be more virulent than other species of coagulase-negative staphylococci. Accurate identification of S simulans isolates would facilitate studies to further define its pathogenic role in human infections.

KW - CoNS = coagulase-negative staphylococcus

KW - CRP = C-reactive protein

KW - ESR = erythrocyte sedimentation rate

KW - MRI = magnetic resonance imaging

KW - PJI = prosthetic joint infection

KW - THA = total hip arthroplasty

KW - WBC = white blood cell

UR - http://www.scopus.com/inward/record.url?scp=0034774789&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034774789&partnerID=8YFLogxK

M3 - Article

C2 - 11605694

AN - SCOPUS:0034774789

VL - 76

SP - 1067

EP - 1070

JO - Mayo Clinic Proceedings

JF - Mayo Clinic Proceedings

SN - 0025-6196

IS - 10

ER -