Abstract
Background In patients with frequent premature ventricular contractions (PVCs), little is known about the profile of PVCs and the outcome of treatment in patients with mitral valve prolapse (MVP) compared to those without MVP. Methods and results Patients with documented PVCs between January 2001 and October 2012 were divided into 2 groups: MVP and non-MVP. The PVC characteristics, efficacy of therapy, and outcome were compared between the 2 groups. A total of 112 patients with MVP and 952 without MVP were identified. The frequency of PVCs was similar between the 2 groups (P > .05). In patients who underwent cardiac mapping, PVCs originating in papillary muscles (26.7% vs 2.3%; P < .001) and fascicle (13.3% vs 3.4%; P < .001) were more frequently seen in the MVP group than in the non-MVP group, which raises the difficulty of catheter ablation. The 2 groups had similar response to catheter ablation or medical therapy (P > .05). The survival rate was similar between the 2 groups (P = .95). Conclusion In patients with significant PVC burden, MVP patients had similar PVC frequency, treatment outcome, and survival rate to those without MVP.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1144-1149 |
| Number of pages | 6 |
| Journal | International Journal of Cardiology |
| Volume | 221 |
| DOIs | |
| State | Published - Oct 15 2016 |
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Keywords
- Antiarrhythmic drug
- Mitral valve prolapse
- Premature ventricular contraction
- Radiofrequency catheter ablation
ASJC Scopus subject areas
- Medicine(all)
- Cardiology and Cardiovascular Medicine
Cite this
Ventricular premature contraction associated with mitral valve prolapse. / Hong-TaoYuan; Yang, Mei; Zhong, Li; Lee, Ying Hsiang; Vaidya, Vaibhav R.; Asirvatham, Samuel J; Ackerman, Michael John; Pislaru, Sorin V.; Suri, Rakesh M.; Slusser, Joshua P.; Hodge, David O.; Wang, Yu Tang; Cha, Yong-Mei.
In: International Journal of Cardiology, Vol. 221, 15.10.2016, p. 1144-1149.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ventricular premature contraction associated with mitral valve prolapse
AU - Hong-TaoYuan,
AU - Yang, Mei
AU - Zhong, Li
AU - Lee, Ying Hsiang
AU - Vaidya, Vaibhav R.
AU - Asirvatham, Samuel J
AU - Ackerman, Michael John
AU - Pislaru, Sorin V.
AU - Suri, Rakesh M.
AU - Slusser, Joshua P.
AU - Hodge, David O.
AU - Wang, Yu Tang
AU - Cha, Yong-Mei
PY - 2016/10/15
Y1 - 2016/10/15
N2 - Background In patients with frequent premature ventricular contractions (PVCs), little is known about the profile of PVCs and the outcome of treatment in patients with mitral valve prolapse (MVP) compared to those without MVP. Methods and results Patients with documented PVCs between January 2001 and October 2012 were divided into 2 groups: MVP and non-MVP. The PVC characteristics, efficacy of therapy, and outcome were compared between the 2 groups. A total of 112 patients with MVP and 952 without MVP were identified. The frequency of PVCs was similar between the 2 groups (P > .05). In patients who underwent cardiac mapping, PVCs originating in papillary muscles (26.7% vs 2.3%; P < .001) and fascicle (13.3% vs 3.4%; P < .001) were more frequently seen in the MVP group than in the non-MVP group, which raises the difficulty of catheter ablation. The 2 groups had similar response to catheter ablation or medical therapy (P > .05). The survival rate was similar between the 2 groups (P = .95). Conclusion In patients with significant PVC burden, MVP patients had similar PVC frequency, treatment outcome, and survival rate to those without MVP.
AB - Background In patients with frequent premature ventricular contractions (PVCs), little is known about the profile of PVCs and the outcome of treatment in patients with mitral valve prolapse (MVP) compared to those without MVP. Methods and results Patients with documented PVCs between January 2001 and October 2012 were divided into 2 groups: MVP and non-MVP. The PVC characteristics, efficacy of therapy, and outcome were compared between the 2 groups. A total of 112 patients with MVP and 952 without MVP were identified. The frequency of PVCs was similar between the 2 groups (P > .05). In patients who underwent cardiac mapping, PVCs originating in papillary muscles (26.7% vs 2.3%; P < .001) and fascicle (13.3% vs 3.4%; P < .001) were more frequently seen in the MVP group than in the non-MVP group, which raises the difficulty of catheter ablation. The 2 groups had similar response to catheter ablation or medical therapy (P > .05). The survival rate was similar between the 2 groups (P = .95). Conclusion In patients with significant PVC burden, MVP patients had similar PVC frequency, treatment outcome, and survival rate to those without MVP.
KW - Antiarrhythmic drug
KW - Mitral valve prolapse
KW - Premature ventricular contraction
KW - Radiofrequency catheter ablation
UR - http://www.scopus.com/inward/record.url?scp=84981241206&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84981241206&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2016.06.252
DO - 10.1016/j.ijcard.2016.06.252
M3 - Article
C2 - 27522301
AN - SCOPUS:84981241206
VL - 221
SP - 1144
EP - 1149
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
ER -