Vascularized composite allotransplant in the realm of regenerative plastic surgery

Harvey Chim, Hatem Amer, Samir Mardini, Steven Lawrence Moran

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Vascularized composite allotransplant (VCA) has led to new treatment options for patients with severe upper extremity and facial injuries. Although VCA can restore form and function, it exposes the patient to the risks associated with lifelong immunosuppression. Hopefully, ongoing advances in regenerative medicine will someday obviate the need for VCA, but until that time, VCA remains an immediate means of reconstructing otherwise unreconstructable defects. We review the outcomes of hand and face transplants, as well as the recent developments in immunosuppression as it relates to the field of VCA.

Original languageEnglish (US)
Pages (from-to)1009-1020
Number of pages12
JournalMayo Clinic Proceedings
Volume89
Issue number7
DOIs
StatePublished - 2014

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Plastic Surgery
Immunosuppression
Facial Transplantation
Facial Injuries
Regenerative Medicine
Upper Extremity
Hand
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vascularized composite allotransplant in the realm of regenerative plastic surgery. / Chim, Harvey; Amer, Hatem; Mardini, Samir; Moran, Steven Lawrence.

In: Mayo Clinic Proceedings, Vol. 89, No. 7, 2014, p. 1009-1020.

Research output: Contribution to journalArticle

Chim, Harvey ; Amer, Hatem ; Mardini, Samir ; Moran, Steven Lawrence. / Vascularized composite allotransplant in the realm of regenerative plastic surgery. In: Mayo Clinic Proceedings. 2014 ; Vol. 89, No. 7. pp. 1009-1020.
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