Variance controlled shear stiffness images for MRE data

J. Mclaughlin, D. Renzi, J. R. Yoon, R. L. Ehman, A. Manduca

Research output: Chapter in Book/Report/Conference proceedingConference contribution

16 Scopus citations

Abstract

In the Magnetic Resonance Elastography experiment we consider a harmonically oscillating mechanical force applied to the boundary surface of a phantom and synchronized with the motion encoding gradient. The phantom is symmetric in the direction of the applied mechanical force and the vector component in that direction decouples from the other components and satisfies a Helmholtz equation. We present a local inversion method to determine the shear wave speed that: (1) treats the phase and amplitude of the data differently; (2) computes derivatives of the data by using statistically justified filtering; and (3) varies filters according to SNR. We test our methods on data from Mayo Clinic and recover the position and stiffness of a 3mm diameter inclusion.

Original languageEnglish (US)
Title of host publication2006 3rd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro - Proceedings
Pages960-963
Number of pages4
StatePublished - Nov 17 2006
Event2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Arlington, VA, United States
Duration: Apr 6 2006Apr 9 2006

Publication series

Name2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
Volume2006

Other

Other2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro
CountryUnited States
CityArlington, VA
Period4/6/064/9/06

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ASJC Scopus subject areas

  • Engineering(all)

Cite this

Mclaughlin, J., Renzi, D., Yoon, J. R., Ehman, R. L., & Manduca, A. (2006). Variance controlled shear stiffness images for MRE data. In 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings (pp. 960-963). [162579] (2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings; Vol. 2006).