Valvular aspects of rheumatic heart disease

Boglarka Remenyi, Ahmed Elguindy, Sidney C. Smith, Magdi Yacoub, David Holmes

Research output: Contribution to journalReview article

32 Citations (Scopus)

Abstract

Acute rheumatic fever and rheumatic heart disease remain major global health problems. Although strategies for primary and secondary prevention are well established, their worldwide implementation is suboptimum. In patients with advanced valvular heart disease, mechanical approaches (both percutaneous and surgical) are well described and can, for selected patients, greatly improve outcomes; however, access to centres with experienced staff is very restricted in regions that have the highest prevalence of disease. Development of diagnostic strategies that can be locally and regionally provided and improve access to expert centres for more advanced disease are urgent and, as yet, unmet clinical needs. We outline current management strategies for valvular rheumatic heart disease on the basis of either strong evidence or expert consensus, and highlight areas needing future research and development.

Original languageEnglish (US)
Pages (from-to)1335-1346
Number of pages12
JournalThe Lancet
Volume387
Issue number10025
DOIs
StatePublished - Mar 26 2016

Fingerprint

Rheumatic Heart Disease
Heart Valve Diseases
Rheumatic Fever
Primary Prevention
Secondary Prevention
Research
Global Health

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Remenyi, B., Elguindy, A., Smith, S. C., Yacoub, M., & Holmes, D. (2016). Valvular aspects of rheumatic heart disease. The Lancet, 387(10025), 1335-1346. https://doi.org/10.1016/S0140-6736(16)00547-X

Valvular aspects of rheumatic heart disease. / Remenyi, Boglarka; Elguindy, Ahmed; Smith, Sidney C.; Yacoub, Magdi; Holmes, David.

In: The Lancet, Vol. 387, No. 10025, 26.03.2016, p. 1335-1346.

Research output: Contribution to journalReview article

Remenyi, B, Elguindy, A, Smith, SC, Yacoub, M & Holmes, D 2016, 'Valvular aspects of rheumatic heart disease', The Lancet, vol. 387, no. 10025, pp. 1335-1346. https://doi.org/10.1016/S0140-6736(16)00547-X
Remenyi B, Elguindy A, Smith SC, Yacoub M, Holmes D. Valvular aspects of rheumatic heart disease. The Lancet. 2016 Mar 26;387(10025):1335-1346. https://doi.org/10.1016/S0140-6736(16)00547-X
Remenyi, Boglarka ; Elguindy, Ahmed ; Smith, Sidney C. ; Yacoub, Magdi ; Holmes, David. / Valvular aspects of rheumatic heart disease. In: The Lancet. 2016 ; Vol. 387, No. 10025. pp. 1335-1346.
@article{8c74523bf2794286bd561118492463f4,
title = "Valvular aspects of rheumatic heart disease",
abstract = "Acute rheumatic fever and rheumatic heart disease remain major global health problems. Although strategies for primary and secondary prevention are well established, their worldwide implementation is suboptimum. In patients with advanced valvular heart disease, mechanical approaches (both percutaneous and surgical) are well described and can, for selected patients, greatly improve outcomes; however, access to centres with experienced staff is very restricted in regions that have the highest prevalence of disease. Development of diagnostic strategies that can be locally and regionally provided and improve access to expert centres for more advanced disease are urgent and, as yet, unmet clinical needs. We outline current management strategies for valvular rheumatic heart disease on the basis of either strong evidence or expert consensus, and highlight areas needing future research and development.",
author = "Boglarka Remenyi and Ahmed Elguindy and Smith, {Sidney C.} and Magdi Yacoub and David Holmes",
year = "2016",
month = "3",
day = "26",
doi = "10.1016/S0140-6736(16)00547-X",
language = "English (US)",
volume = "387",
pages = "1335--1346",
journal = "The Lancet",
issn = "0140-6736",
publisher = "Elsevier Limited",
number = "10025",

}

TY - JOUR

T1 - Valvular aspects of rheumatic heart disease

AU - Remenyi, Boglarka

AU - Elguindy, Ahmed

AU - Smith, Sidney C.

AU - Yacoub, Magdi

AU - Holmes, David

PY - 2016/3/26

Y1 - 2016/3/26

N2 - Acute rheumatic fever and rheumatic heart disease remain major global health problems. Although strategies for primary and secondary prevention are well established, their worldwide implementation is suboptimum. In patients with advanced valvular heart disease, mechanical approaches (both percutaneous and surgical) are well described and can, for selected patients, greatly improve outcomes; however, access to centres with experienced staff is very restricted in regions that have the highest prevalence of disease. Development of diagnostic strategies that can be locally and regionally provided and improve access to expert centres for more advanced disease are urgent and, as yet, unmet clinical needs. We outline current management strategies for valvular rheumatic heart disease on the basis of either strong evidence or expert consensus, and highlight areas needing future research and development.

AB - Acute rheumatic fever and rheumatic heart disease remain major global health problems. Although strategies for primary and secondary prevention are well established, their worldwide implementation is suboptimum. In patients with advanced valvular heart disease, mechanical approaches (both percutaneous and surgical) are well described and can, for selected patients, greatly improve outcomes; however, access to centres with experienced staff is very restricted in regions that have the highest prevalence of disease. Development of diagnostic strategies that can be locally and regionally provided and improve access to expert centres for more advanced disease are urgent and, as yet, unmet clinical needs. We outline current management strategies for valvular rheumatic heart disease on the basis of either strong evidence or expert consensus, and highlight areas needing future research and development.

UR - http://www.scopus.com/inward/record.url?scp=84962259716&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84962259716&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(16)00547-X

DO - 10.1016/S0140-6736(16)00547-X

M3 - Review article

C2 - 27025439

AN - SCOPUS:84962259716

VL - 387

SP - 1335

EP - 1346

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 10025

ER -