Validación de la escala abreviada de síntomas en pacientes con neoplasias mieloproliferativas (MPN-SAF-TSS): Evaluación en pacientes colombianos

Translated title of the contribution: Validation of the abbreviated symptom scale for patients with myeloproliferative Neoplasm (MPN-SAF-TSS): Evaluation for Colombian patients

Teófilo Lozano, Carolina Wiesner, Rubén Mesa, Marie Emanuel Robyn, Martha Suárez, Edgar Salguero

Research output: Contribution to journalArticle


Objective. To validate in Colombia the abbreviated scale of representative symptoms of myeloproliferative neoplasms, for further use in research and for application in the clinical setting. Materials and methods. A cross-cultural adaptation of the mpn-saf Tss-scale (mieloproliferative neoplasm symptom assessment form total symptom score) to Colombian Spanish using statistical validity and reliability analysis with a specific sample size for each psychometric property. Results. Based on the psychometric properties, the verification of reliability and internal structure with a Cronbach’s alpha scale of 0.8552 was achieved, denoting good internal consistency. A Lin’s concordance correlation coefficient of 0.765 was obtained, showing good reliability; factor analysis showed multiple correlation coefficient values above 0.3, indicating that the scale variables measure common factors. Concurrent validity determines that the scale measures what it should measure with an adequate Spearman correlation coefficient of -0.71 and -0.73 when confronted with the FAciT-Fatigue and Fact-Lym scales, respectively. Conclusion: The mpn-saf-tss scale adapted to Colombian Spanish is a valid assessment instrument for symptoms in patients with myeloproliferative neoplasms and can be used in clinical practice or trials due to its adequate psychometric properties.

Original languageSpanish
Pages (from-to)325-334
Number of pages10
JournalRevista Ciencias de la Salud
Issue number3
StatePublished - 2017



  • Myeloproliferative disorders
  • Quality of life
  • Symptom assessment
  • Validation study

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Health(social science)

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