TY - JOUR
T1 - Validation of Single-Item Linear Analog Scale Assessment of Quality of Life in Neuro-Oncology Patients
AU - Locke, Dona E.C.
AU - Decker, Paul A.
AU - Sloan, Jeff A.
AU - Brown, Paul D.
AU - Malec, James F.
AU - Clark, Matthew M.
AU - Rummans, Teresa A.
AU - Ballman, Karla V.
AU - Schaefer, Paul L.
AU - Buckner, Jan C.
PY - 2007/12
Y1 - 2007/12
N2 - Assessment of patient quality of life (QOL) requires balancing the details provided by multi-item assessments with the reduced burden of single-item assessments. In this project, we investigated the psychometric properties of single-item Linear Analog Scale Assessments (LASAs) for patients with newly diagnosed high-grade gliomas. Measures included QOL LASAs (overall, physical, emotional, spiritual, intellectual), Symptom Distress Scale (SDS), Profile of Mood States (POMS; overall, confusion, fatigue), and Functional Assessment of Cancer Therapy-Brain (FACT-Br; overall, brain, physical, emotional). Associations of LASA measures with SDS, POMS, and FACT-Br domains and with Eastern Cooperative Oncology Group performance score (PS) and Mini-Mental State Examination (MMSE) were assessed. Repeated measures ANOVA models compared the change over time of LASAs and SDS, POMS, and FACT-Br. Two hundred five patients completed the assessments across three time points. To allow comparison across measures, all scores were converted to a scale of 0-100, with higher scores indicating better QOL. LASA mean scores ranged from 60 to 78; SDS, POMS, and FACT-Br ranged from 62 to 81. FACT-Br physical (P < 0.001) and POMS fatigue subscale (P = 0.005) decreased over time, as did LASA physical (P = 0.08). LASA scales were strongly associated with corresponding scales on SDS, POMS, and FACT-Br (0.44 < rho < 0.65; P < 0.001). LASA was negatively associated with PS and positively with MMSE, with associations similar in magnitude to the other QOL and psychosocial measures. The data suggest that the single-item LASA scales are valid for assessing QOL of cancer patients and are an appropriate alternative when a shorter instrument is warranted.
AB - Assessment of patient quality of life (QOL) requires balancing the details provided by multi-item assessments with the reduced burden of single-item assessments. In this project, we investigated the psychometric properties of single-item Linear Analog Scale Assessments (LASAs) for patients with newly diagnosed high-grade gliomas. Measures included QOL LASAs (overall, physical, emotional, spiritual, intellectual), Symptom Distress Scale (SDS), Profile of Mood States (POMS; overall, confusion, fatigue), and Functional Assessment of Cancer Therapy-Brain (FACT-Br; overall, brain, physical, emotional). Associations of LASA measures with SDS, POMS, and FACT-Br domains and with Eastern Cooperative Oncology Group performance score (PS) and Mini-Mental State Examination (MMSE) were assessed. Repeated measures ANOVA models compared the change over time of LASAs and SDS, POMS, and FACT-Br. Two hundred five patients completed the assessments across three time points. To allow comparison across measures, all scores were converted to a scale of 0-100, with higher scores indicating better QOL. LASA mean scores ranged from 60 to 78; SDS, POMS, and FACT-Br ranged from 62 to 81. FACT-Br physical (P < 0.001) and POMS fatigue subscale (P = 0.005) decreased over time, as did LASA physical (P = 0.08). LASA scales were strongly associated with corresponding scales on SDS, POMS, and FACT-Br (0.44 < rho < 0.65; P < 0.001). LASA was negatively associated with PS and positively with MMSE, with associations similar in magnitude to the other QOL and psychosocial measures. The data suggest that the single-item LASA scales are valid for assessing QOL of cancer patients and are an appropriate alternative when a shorter instrument is warranted.
KW - LASA
KW - Quality of life
KW - measurement
KW - neuro-oncology
KW - validation
UR - http://www.scopus.com/inward/record.url?scp=36349008586&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36349008586&partnerID=8YFLogxK
U2 - 10.1016/j.jpainsymman.2007.01.016
DO - 10.1016/j.jpainsymman.2007.01.016
M3 - Article
C2 - 17703910
AN - SCOPUS:36349008586
SN - 0885-3924
VL - 34
SP - 628
EP - 638
JO - Journal of pain and symptom management
JF - Journal of pain and symptom management
IS - 6
ER -