Validation of liquid chromatography-tandem mass spectrometry method for analysis of urinary conjugated metanephrine and normetanephrine for screening of pheochromocytoma

Medicine & Life Sciences

• Normetanephrine 95%
• Metanephrine 93%
• Pheochromocytoma 69%
• Tandem Mass Spectrometry 68%
• Liquid Chromatography 64%
• Urine 22%
• High Pressure Liquid Chromatography 17%
• Solid Phase Extraction 14%
• Paraganglioma 13%
• Adrenal Medulla 13%
• Amides 12%
• Gas Chromatography-Mass Spectrometry 12%
• Neural Crest 12%
• Isotopes 11%
• Limit of Detection 10%
• Methanol 10%
• Calibration 10%
• Baths 10%
• Immunoassay 10%
• Neuroblastoma 10%
• Tumor Biomarkers 10%
• Sensitivity and Specificity 7%
• Water 6%
• Pharmaceutical Preparations 4%
• Neoplasms 3%

Chemical Compounds

• Metanephrine 100%
• Normetanephrine 99%
• Biochemical Marker 19%
• Stable Isotope 13%
• Immunoassay 11%
• Analytical Calibration 10%
• Tandem Mass Spectrometry 10%
• Gas Chromatography Mass Spectrometry (GCMS) 9%
• Amide 8%
• Methanol 7%
• Column Like Crystal 7%
• Drug 6%
• Time 4%