Validation of dual-source single-tube reconstruction as a method to obtain half-dose images to evaluate radiation dose and noise reduction

Phantom and human assessment using CT colonography and sinogram-affirmed iterative reconstruction (SAFIRE)

Joel Garland Fletcher, Katharine L R Grant, Jeff L. Fidler, Maria Shiung, Lifeng Yu, Jia Wang, Bernhard Schmidt, Thomas Allmendinger, Cynthia H McCollough

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

OBJECTIVE: To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT. METHODS: Phantoms of varying sizes were scanned at multiple tube potentials using dose-matched dual-source (DS) and single-source (SS) protocols. Images from single-tube reconstruction of DS data were compared with SS images acquired at half-original CTDIvol. Thirty patients underwent supine SS and dose-matched prone DS CT colonography (CTC). Half-dose prone images were reconstructed with sinogram-affirmed iterative reconstruction (SAFIRE). Two radiologists scored image quality on 2-dimensional (2D) and 3D images. RESULTS: Image noise was similar between half-dose SS images and DS images reconstructed from one tube only with tube potential of 120 kV or more for phantoms 40 cm or smaller (P < 0.05). For both readers, the patients' CTC image quality scores were more than 84% concordant between SS or DS CTC images, and half-dose-prone CTC images with SAFIRE had 84% or more concordance with routine-dose CTC except for 3D image noise. CONCLUSIONS: In appropriately sized patients, DS acquisition with single-tube reconstruction can create half-dose images, permitting comparison to full-dose images. For CTC, there is comparable image quality for colonic evaluation between full-dose and half-dose images reconstructed with SAFIRE.

Original languageEnglish (US)
Pages (from-to)560-569
Number of pages10
JournalJournal of Computer Assisted Tomography
Volume36
Issue number5
DOIs
StatePublished - Sep 2012

Fingerprint

Computed Tomographic Colonography
Noise
Radiation
Information Storage and Retrieval

Keywords

  • CT colonography
  • dose reduction
  • noise reduction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

@article{964e61e4cc5b4d25a3a6f6c899b9648e,
title = "Validation of dual-source single-tube reconstruction as a method to obtain half-dose images to evaluate radiation dose and noise reduction: Phantom and human assessment using CT colonography and sinogram-affirmed iterative reconstruction (SAFIRE)",
abstract = "OBJECTIVE: To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT. METHODS: Phantoms of varying sizes were scanned at multiple tube potentials using dose-matched dual-source (DS) and single-source (SS) protocols. Images from single-tube reconstruction of DS data were compared with SS images acquired at half-original CTDIvol. Thirty patients underwent supine SS and dose-matched prone DS CT colonography (CTC). Half-dose prone images were reconstructed with sinogram-affirmed iterative reconstruction (SAFIRE). Two radiologists scored image quality on 2-dimensional (2D) and 3D images. RESULTS: Image noise was similar between half-dose SS images and DS images reconstructed from one tube only with tube potential of 120 kV or more for phantoms 40 cm or smaller (P < 0.05). For both readers, the patients' CTC image quality scores were more than 84{\%} concordant between SS or DS CTC images, and half-dose-prone CTC images with SAFIRE had 84{\%} or more concordance with routine-dose CTC except for 3D image noise. CONCLUSIONS: In appropriately sized patients, DS acquisition with single-tube reconstruction can create half-dose images, permitting comparison to full-dose images. For CTC, there is comparable image quality for colonic evaluation between full-dose and half-dose images reconstructed with SAFIRE.",
keywords = "CT colonography, dose reduction, noise reduction",
author = "Fletcher, {Joel Garland} and Grant, {Katharine L R} and Fidler, {Jeff L.} and Maria Shiung and Lifeng Yu and Jia Wang and Bernhard Schmidt and Thomas Allmendinger and McCollough, {Cynthia H}",
year = "2012",
month = "9",
doi = "10.1097/RCT.0b013e318263cc1b",
language = "English (US)",
volume = "36",
pages = "560--569",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Validation of dual-source single-tube reconstruction as a method to obtain half-dose images to evaluate radiation dose and noise reduction

T2 - Phantom and human assessment using CT colonography and sinogram-affirmed iterative reconstruction (SAFIRE)

AU - Fletcher, Joel Garland

AU - Grant, Katharine L R

AU - Fidler, Jeff L.

AU - Shiung, Maria

AU - Yu, Lifeng

AU - Wang, Jia

AU - Schmidt, Bernhard

AU - Allmendinger, Thomas

AU - McCollough, Cynthia H

PY - 2012/9

Y1 - 2012/9

N2 - OBJECTIVE: To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT. METHODS: Phantoms of varying sizes were scanned at multiple tube potentials using dose-matched dual-source (DS) and single-source (SS) protocols. Images from single-tube reconstruction of DS data were compared with SS images acquired at half-original CTDIvol. Thirty patients underwent supine SS and dose-matched prone DS CT colonography (CTC). Half-dose prone images were reconstructed with sinogram-affirmed iterative reconstruction (SAFIRE). Two radiologists scored image quality on 2-dimensional (2D) and 3D images. RESULTS: Image noise was similar between half-dose SS images and DS images reconstructed from one tube only with tube potential of 120 kV or more for phantoms 40 cm or smaller (P < 0.05). For both readers, the patients' CTC image quality scores were more than 84% concordant between SS or DS CTC images, and half-dose-prone CTC images with SAFIRE had 84% or more concordance with routine-dose CTC except for 3D image noise. CONCLUSIONS: In appropriately sized patients, DS acquisition with single-tube reconstruction can create half-dose images, permitting comparison to full-dose images. For CTC, there is comparable image quality for colonic evaluation between full-dose and half-dose images reconstructed with SAFIRE.

AB - OBJECTIVE: To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT. METHODS: Phantoms of varying sizes were scanned at multiple tube potentials using dose-matched dual-source (DS) and single-source (SS) protocols. Images from single-tube reconstruction of DS data were compared with SS images acquired at half-original CTDIvol. Thirty patients underwent supine SS and dose-matched prone DS CT colonography (CTC). Half-dose prone images were reconstructed with sinogram-affirmed iterative reconstruction (SAFIRE). Two radiologists scored image quality on 2-dimensional (2D) and 3D images. RESULTS: Image noise was similar between half-dose SS images and DS images reconstructed from one tube only with tube potential of 120 kV or more for phantoms 40 cm or smaller (P < 0.05). For both readers, the patients' CTC image quality scores were more than 84% concordant between SS or DS CTC images, and half-dose-prone CTC images with SAFIRE had 84% or more concordance with routine-dose CTC except for 3D image noise. CONCLUSIONS: In appropriately sized patients, DS acquisition with single-tube reconstruction can create half-dose images, permitting comparison to full-dose images. For CTC, there is comparable image quality for colonic evaluation between full-dose and half-dose images reconstructed with SAFIRE.

KW - CT colonography

KW - dose reduction

KW - noise reduction

UR - http://www.scopus.com/inward/record.url?scp=84866673170&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866673170&partnerID=8YFLogxK

U2 - 10.1097/RCT.0b013e318263cc1b

DO - 10.1097/RCT.0b013e318263cc1b

M3 - Article

VL - 36

SP - 560

EP - 569

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

SN - 0363-8715

IS - 5

ER -