Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis

Nicolas Reina; William H. Trousdale; Christopher G. Salib; Loribeth Q. Evertz; Lawrence J. Berglund; Andre J. van Wijnen; Timothy E. Hewett; Charlotte E. Berry; Daniel J. Berry; Mark E. Morrey; Joaquin Sanchez-Sotelo; Matthew P. Abdel

doi:10.1002/jor.23884

Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis

Nicolas Reina, William H. Trousdale, Christopher G. Salib, Loribeth Q. Evertz, Lawrence J. Berglund, Andre J. van Wijnen, Timothy E. Hewett, Charlotte E. Berry, Daniel J. Berry, Mark E. Morrey, Joaquin Sanchez-Sotelo, Matthew P. Abdel

Orthopedic Surgery

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The current method of measuring arthrofibrosis in live rabbits is critically limited. Specifically, this method involves radioactive fluoroscopy, error-prone goniometric measurements, and static joint angle outcomes that fail to approximate the compliance of tissues surrounding the joint. This study aims to validate a novel method of capturing the compliance of contracted tissues surrounding the joint without the use of fluoroscopy or animal sacrifice. Surgically induced contractures of one-hundred and eight rabbits were measured using the current standard of contracture measurement (a pulley system) as well as a newly designed dynamic load cell (DLC) device. The DLC device was highly reliable when compared to the pulley system (r = 0.907, p < 0.001). Finally, the DLC device produced joint stiffness hysteresis curves capable of approximating the compliance of stiff joint tissues, ultimately calculating a mean joint stiffness of 1.57 ± 1.31 N · m · rad ⁻¹ (range, 0.33–6.37 N · m · rad ⁻¹ ). In conclusion, the DLC device represents a valid method for measuring joint contractures. Further, the DLC device notably improves current techniques by introducing the capacity to approximate the compliance of contracted tissues in living rabbits.

Original language	English (US)
Pages (from-to)	2186-2192
Number of pages	7
Journal	Journal of Orthopaedic Research
Volume	36
Issue number	8
DOIs	https://doi.org/10.1002/jor.23884
State	Published - Aug 2018

Keywords

arthrofibrosis
joint contracture
knee biomechanics
rabbit model

ASJC Scopus subject areas

Orthopedics and Sports Medicine

Access to Document

10.1002/jor.23884

Cite this

Reina, N., Trousdale, W. H., Salib, C. G., Evertz, L. Q., Berglund, L. J., van Wijnen, A. J., Hewett, T. E., Berry, C. E., Berry, D. J., Morrey, M. E., Sanchez-Sotelo, J., & Abdel, M. P. (2018). Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis. Journal of Orthopaedic Research, 36(8), 2186-2192. https://doi.org/10.1002/jor.23884

@article{f77f571b9c154ffdbbd6517739968b16,

title = "Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis",

abstract = " The current method of measuring arthrofibrosis in live rabbits is critically limited. Specifically, this method involves radioactive fluoroscopy, error-prone goniometric measurements, and static joint angle outcomes that fail to approximate the compliance of tissues surrounding the joint. This study aims to validate a novel method of capturing the compliance of contracted tissues surrounding the joint without the use of fluoroscopy or animal sacrifice. Surgically induced contractures of one-hundred and eight rabbits were measured using the current standard of contracture measurement (a pulley system) as well as a newly designed dynamic load cell (DLC) device. The DLC device was highly reliable when compared to the pulley system (r = 0.907, p < 0.001). Finally, the DLC device produced joint stiffness hysteresis curves capable of approximating the compliance of stiff joint tissues, ultimately calculating a mean joint stiffness of 1.57 ± 1.31 N · m · rad −1 (range, 0.33–6.37 N · m · rad −1 ). In conclusion, the DLC device represents a valid method for measuring joint contractures. Further, the DLC device notably improves current techniques by introducing the capacity to approximate the compliance of contracted tissues in living rabbits.",

keywords = "arthrofibrosis, joint contracture, knee biomechanics, rabbit model",

author = "Nicolas Reina and Trousdale, {William H.} and Salib, {Christopher G.} and Evertz, {Loribeth Q.} and Berglund, {Lawrence J.} and {van Wijnen}, {Andre J.} and Hewett, {Timothy E.} and Berry, {Charlotte E.} and Berry, {Daniel J.} and Morrey, {Mark E.} and Joaquin Sanchez-Sotelo and Abdel, {Matthew P.}",

note = "Publisher Copyright: {\textcopyright} 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.",

year = "2018",

month = aug,

doi = "10.1002/jor.23884",

language = "English (US)",

volume = "36",

pages = "2186--2192",

journal = "Journal of Orthopaedic Research",

issn = "0736-0266",

publisher = "John Wiley and Sons Inc.",

number = "8",

}

TY - JOUR

T1 - Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis

AU - Reina, Nicolas

AU - Trousdale, William H.

AU - Salib, Christopher G.

AU - Evertz, Loribeth Q.

AU - Berglund, Lawrence J.

AU - van Wijnen, Andre J.

AU - Hewett, Timothy E.

AU - Berry, Charlotte E.

AU - Berry, Daniel J.

AU - Morrey, Mark E.

AU - Sanchez-Sotelo, Joaquin

AU - Abdel, Matthew P.

PY - 2018/8

Y1 - 2018/8

N2 - The current method of measuring arthrofibrosis in live rabbits is critically limited. Specifically, this method involves radioactive fluoroscopy, error-prone goniometric measurements, and static joint angle outcomes that fail to approximate the compliance of tissues surrounding the joint. This study aims to validate a novel method of capturing the compliance of contracted tissues surrounding the joint without the use of fluoroscopy or animal sacrifice. Surgically induced contractures of one-hundred and eight rabbits were measured using the current standard of contracture measurement (a pulley system) as well as a newly designed dynamic load cell (DLC) device. The DLC device was highly reliable when compared to the pulley system (r = 0.907, p < 0.001). Finally, the DLC device produced joint stiffness hysteresis curves capable of approximating the compliance of stiff joint tissues, ultimately calculating a mean joint stiffness of 1.57 ± 1.31 N · m · rad −1 (range, 0.33–6.37 N · m · rad −1 ). In conclusion, the DLC device represents a valid method for measuring joint contractures. Further, the DLC device notably improves current techniques by introducing the capacity to approximate the compliance of contracted tissues in living rabbits.

AB - The current method of measuring arthrofibrosis in live rabbits is critically limited. Specifically, this method involves radioactive fluoroscopy, error-prone goniometric measurements, and static joint angle outcomes that fail to approximate the compliance of tissues surrounding the joint. This study aims to validate a novel method of capturing the compliance of contracted tissues surrounding the joint without the use of fluoroscopy or animal sacrifice. Surgically induced contractures of one-hundred and eight rabbits were measured using the current standard of contracture measurement (a pulley system) as well as a newly designed dynamic load cell (DLC) device. The DLC device was highly reliable when compared to the pulley system (r = 0.907, p < 0.001). Finally, the DLC device produced joint stiffness hysteresis curves capable of approximating the compliance of stiff joint tissues, ultimately calculating a mean joint stiffness of 1.57 ± 1.31 N · m · rad −1 (range, 0.33–6.37 N · m · rad −1 ). In conclusion, the DLC device represents a valid method for measuring joint contractures. Further, the DLC device notably improves current techniques by introducing the capacity to approximate the compliance of contracted tissues in living rabbits.

KW - arthrofibrosis

KW - joint contracture

KW - knee biomechanics

KW - rabbit model

UR - http://www.scopus.com/inward/record.url?scp=85044326239&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044326239&partnerID=8YFLogxK

U2 - 10.1002/jor.23884

DO - 10.1002/jor.23884

M3 - Article

C2 - 29473666

AN - SCOPUS:85044326239

SN - 0736-0266

VL - 36

SP - 2186

EP - 2192

JO - Journal of Orthopaedic Research

JF - Journal of Orthopaedic Research

IS - 8

ER -

Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this