Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis

Nicolas Reina, William H. Trousdale, Christopher G. Salib, Loribeth Q. Evertz, Lawrence J. Berglund, Andre J van Wijnen, Timothy Hewett, Charlotte E. Berry, Daniel J. Berry, Mark E. Morrey, Joaquin Sanchez-Sotelo, Matthew Abdel

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The current method of measuring arthrofibrosis in live rabbits is critically limited. Specifically, this method involves radioactive fluoroscopy, error-prone goniometric measurements, and static joint angle outcomes that fail to approximate the compliance of tissues surrounding the joint. This study aims to validate a novel method of capturing the compliance of contracted tissues surrounding the joint without the use of fluoroscopy or animal sacrifice. Surgically induced contractures of one-hundred and eight rabbits were measured using the current standard of contracture measurement (a pulley system) as well as a newly designed dynamic load cell (DLC) device. The DLC device was highly reliable when compared to the pulley system (r=0.907, p<0.001). Finally, the DLC device produced joint stiffness hysteresis curves capable of approximating the compliance of stiff joint tissues, ultimately calculating a mean joint stiffness of 1.57±1.31N·m·rad-1 (range, 0.33-6.37N·m·rad-1). In conclusion, the DLC device represents a valid method for measuring joint contractures. Further, the DLC device notably improves current techniques by introducing the capacity to approximate the compliance of contracted tissues in living rabbits.

Original languageEnglish (US)
JournalJournal of Orthopaedic Research
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Contracture
Joints
Rabbits
Equipment and Supplies
Compliance
Fluoroscopy

Keywords

  • Arthrofibrosis
  • Joint contracture
  • Knee biomechanics
  • Rabbit model

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis. / Reina, Nicolas; Trousdale, William H.; Salib, Christopher G.; Evertz, Loribeth Q.; Berglund, Lawrence J.; van Wijnen, Andre J; Hewett, Timothy; Berry, Charlotte E.; Berry, Daniel J.; Morrey, Mark E.; Sanchez-Sotelo, Joaquin; Abdel, Matthew.

In: Journal of Orthopaedic Research, 01.01.2018.

Research output: Contribution to journalArticle

Reina, N, Trousdale, WH, Salib, CG, Evertz, LQ, Berglund, LJ, van Wijnen, AJ, Hewett, T, Berry, CE, Berry, DJ, Morrey, ME, Sanchez-Sotelo, J & Abdel, M 2018, 'Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis', Journal of Orthopaedic Research. https://doi.org/10.1002/jor.23884
Reina, Nicolas ; Trousdale, William H. ; Salib, Christopher G. ; Evertz, Loribeth Q. ; Berglund, Lawrence J. ; van Wijnen, Andre J ; Hewett, Timothy ; Berry, Charlotte E. ; Berry, Daniel J. ; Morrey, Mark E. ; Sanchez-Sotelo, Joaquin ; Abdel, Matthew. / Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis. In: Journal of Orthopaedic Research. 2018.
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