TY - JOUR
T1 - Vagus nerve stimulation for epilepsy
T2 - Randomized comparison of three stimulation paradigms
AU - DeGiorgio, Christopher
AU - Heck, C.
AU - Bunch, S.
AU - Britton, J.
AU - Green, P.
AU - Lancman, M.
AU - Murphy, J.
AU - Olejniczak, P.
AU - Shih, J.
AU - Arrambide, S.
AU - Soss, J.
N1 - Funding Information:
Supported by a grant from Cyberonics, Inc.
PY - 2005/7/26
Y1 - 2005/7/26
N2 - Vagus nerve stimulation (VNS) is an effective adjunctive treatment for intractable epilepsy. However, the optimal range of device duty-cycles [on/ (on + off times)] is poorly understood. The authors performed a multicenter, randomized trial of three unique modes of VNS, which varied primarily by duty-cycle. The results indicate that the three duty-cycles were equally effective. The data support the use of standard duty-cycles as initial therapy.
AB - Vagus nerve stimulation (VNS) is an effective adjunctive treatment for intractable epilepsy. However, the optimal range of device duty-cycles [on/ (on + off times)] is poorly understood. The authors performed a multicenter, randomized trial of three unique modes of VNS, which varied primarily by duty-cycle. The results indicate that the three duty-cycles were equally effective. The data support the use of standard duty-cycles as initial therapy.
UR - http://www.scopus.com/inward/record.url?scp=85026136988&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85026136988&partnerID=8YFLogxK
U2 - 10.1212/01.wnl.0000168899.11598.00
DO - 10.1212/01.wnl.0000168899.11598.00
M3 - Article
C2 - 16043810
AN - SCOPUS:85026136988
SN - 0028-3878
VL - 65
SP - 317
EP - 319
JO - Neurology
JF - Neurology
IS - 2
ER -