Vagus nerve stimulation for epilepsy: Randomized comparison of three stimulation paradigms

Christopher DeGiorgio, C. Heck, S. Bunch, J. Britton, P. Green, M. Lancman, J. Murphy, P. Olejniczak, J. Shih, S. Arrambide, J. Soss

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Vagus nerve stimulation (VNS) is an effective adjunctive treatment for intractable epilepsy. However, the optimal range of device duty-cycles [on/ (on + off times)] is poorly understood. The authors performed a multicenter, randomized trial of three unique modes of VNS, which varied primarily by duty-cycle. The results indicate that the three duty-cycles were equally effective. The data support the use of standard duty-cycles as initial therapy.

Original languageEnglish (US)
Pages (from-to)317-319
Number of pages3
JournalNeurology
Volume65
Issue number2
DOIs
StatePublished - Jul 26 2005

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Vagus Nerve Stimulation
Epilepsy
Multicenter Studies
Equipment and Supplies
Therapeutics
Drug Resistant Epilepsy

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

DeGiorgio, C., Heck, C., Bunch, S., Britton, J., Green, P., Lancman, M., ... Soss, J. (2005). Vagus nerve stimulation for epilepsy: Randomized comparison of three stimulation paradigms. Neurology, 65(2), 317-319. https://doi.org/10.1212/01.wnl.0000168899.11598.00

Vagus nerve stimulation for epilepsy : Randomized comparison of three stimulation paradigms. / DeGiorgio, Christopher; Heck, C.; Bunch, S.; Britton, J.; Green, P.; Lancman, M.; Murphy, J.; Olejniczak, P.; Shih, J.; Arrambide, S.; Soss, J.

In: Neurology, Vol. 65, No. 2, 26.07.2005, p. 317-319.

Research output: Contribution to journalArticle

DeGiorgio, C, Heck, C, Bunch, S, Britton, J, Green, P, Lancman, M, Murphy, J, Olejniczak, P, Shih, J, Arrambide, S & Soss, J 2005, 'Vagus nerve stimulation for epilepsy: Randomized comparison of three stimulation paradigms', Neurology, vol. 65, no. 2, pp. 317-319. https://doi.org/10.1212/01.wnl.0000168899.11598.00
DeGiorgio, Christopher ; Heck, C. ; Bunch, S. ; Britton, J. ; Green, P. ; Lancman, M. ; Murphy, J. ; Olejniczak, P. ; Shih, J. ; Arrambide, S. ; Soss, J. / Vagus nerve stimulation for epilepsy : Randomized comparison of three stimulation paradigms. In: Neurology. 2005 ; Vol. 65, No. 2. pp. 317-319.
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