Usefulness of asthma predictive index in ascertaining asthma status of children using medical records: An explorative study

C. I. Wi, E. A. Krusemark, G. Voge, Sunghwan Sohn, Hongfang D Liu, Euijung Ryu, Miguel Park, J. A. Castro-Rodriguez, Young J Juhn

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Frequent wheezing in original asthma predictive index (API) was defined by parental report of recurrent wheezing within 1 year during the first 3 years of life. The nature of frequent wheezing in children, particularly aged over 3 years, has not been studied. We aimed to assess the frequency and interval of wheezing to define frequent wheezing in ascertaining asthma for children using medical records. Methods: Among children who participated in a previous study (n = 427), all wheezing episodes documented in medical records were collected for children who had ≥2 wheezing episodes PLUS met one major criterion or two minor criteria of API. We compared the distribution of known risk factors for asthma between subjects having two consecutive wheezing episodes with shorter interval (≤1 year) compared to those with longer interval (1 to 3 years). Results: A total of 62 children met API at median age of 2.3 years. During follow-up period (median age: 11.3 years), a total of 198 wheezing episodes were observed. 81% of wheezing intervals were within 3 years from the earlier wheezing episode, including 60% within 1 year. Children who met API based on 1-year interval (n = 40) vs 1- to 3-year interval (n = 13) appeared to be similar in regard to the known risk factors for asthma. Conclusions: Our exploratory study finding suggests that children who had frequent wheezing episodes with longer interval (<3 years) need to be considered to be determined as asthma cases when API is applied to retrospective medical records. Prospective studies with a larger sample size need to replicate this finding.

Original languageEnglish (US)
JournalAllergy: European Journal of Allergy and Clinical Immunology
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Respiratory Sounds
Medical Records
Asthma
Sample Size
Prospective Studies

Keywords

  • Asthma predictive index
  • Heterogeneity
  • Medical records
  • Retrospective studies
  • Wheezing

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

@article{f4dd6aa8f33e44fe99dc6106eed3382f,
title = "Usefulness of asthma predictive index in ascertaining asthma status of children using medical records: An explorative study",
abstract = "Background: Frequent wheezing in original asthma predictive index (API) was defined by parental report of recurrent wheezing within 1 year during the first 3 years of life. The nature of frequent wheezing in children, particularly aged over 3 years, has not been studied. We aimed to assess the frequency and interval of wheezing to define frequent wheezing in ascertaining asthma for children using medical records. Methods: Among children who participated in a previous study (n = 427), all wheezing episodes documented in medical records were collected for children who had ≥2 wheezing episodes PLUS met one major criterion or two minor criteria of API. We compared the distribution of known risk factors for asthma between subjects having two consecutive wheezing episodes with shorter interval (≤1 year) compared to those with longer interval (1 to 3 years). Results: A total of 62 children met API at median age of 2.3 years. During follow-up period (median age: 11.3 years), a total of 198 wheezing episodes were observed. 81{\%} of wheezing intervals were within 3 years from the earlier wheezing episode, including 60{\%} within 1 year. Children who met API based on 1-year interval (n = 40) vs 1- to 3-year interval (n = 13) appeared to be similar in regard to the known risk factors for asthma. Conclusions: Our exploratory study finding suggests that children who had frequent wheezing episodes with longer interval (<3 years) need to be considered to be determined as asthma cases when API is applied to retrospective medical records. Prospective studies with a larger sample size need to replicate this finding.",
keywords = "Asthma predictive index, Heterogeneity, Medical records, Retrospective studies, Wheezing",
author = "Wi, {C. I.} and Krusemark, {E. A.} and G. Voge and Sunghwan Sohn and Liu, {Hongfang D} and Euijung Ryu and Miguel Park and Castro-Rodriguez, {J. A.} and Juhn, {Young J}",
year = "2018",
month = "1",
day = "1",
doi = "10.1111/all.13403",
language = "English (US)",
journal = "Allergy: European Journal of Allergy and Clinical Immunology",
issn = "0105-4538",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Usefulness of asthma predictive index in ascertaining asthma status of children using medical records

T2 - An explorative study

AU - Wi, C. I.

AU - Krusemark, E. A.

AU - Voge, G.

AU - Sohn, Sunghwan

AU - Liu, Hongfang D

AU - Ryu, Euijung

AU - Park, Miguel

AU - Castro-Rodriguez, J. A.

AU - Juhn, Young J

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: Frequent wheezing in original asthma predictive index (API) was defined by parental report of recurrent wheezing within 1 year during the first 3 years of life. The nature of frequent wheezing in children, particularly aged over 3 years, has not been studied. We aimed to assess the frequency and interval of wheezing to define frequent wheezing in ascertaining asthma for children using medical records. Methods: Among children who participated in a previous study (n = 427), all wheezing episodes documented in medical records were collected for children who had ≥2 wheezing episodes PLUS met one major criterion or two minor criteria of API. We compared the distribution of known risk factors for asthma between subjects having two consecutive wheezing episodes with shorter interval (≤1 year) compared to those with longer interval (1 to 3 years). Results: A total of 62 children met API at median age of 2.3 years. During follow-up period (median age: 11.3 years), a total of 198 wheezing episodes were observed. 81% of wheezing intervals were within 3 years from the earlier wheezing episode, including 60% within 1 year. Children who met API based on 1-year interval (n = 40) vs 1- to 3-year interval (n = 13) appeared to be similar in regard to the known risk factors for asthma. Conclusions: Our exploratory study finding suggests that children who had frequent wheezing episodes with longer interval (<3 years) need to be considered to be determined as asthma cases when API is applied to retrospective medical records. Prospective studies with a larger sample size need to replicate this finding.

AB - Background: Frequent wheezing in original asthma predictive index (API) was defined by parental report of recurrent wheezing within 1 year during the first 3 years of life. The nature of frequent wheezing in children, particularly aged over 3 years, has not been studied. We aimed to assess the frequency and interval of wheezing to define frequent wheezing in ascertaining asthma for children using medical records. Methods: Among children who participated in a previous study (n = 427), all wheezing episodes documented in medical records were collected for children who had ≥2 wheezing episodes PLUS met one major criterion or two minor criteria of API. We compared the distribution of known risk factors for asthma between subjects having two consecutive wheezing episodes with shorter interval (≤1 year) compared to those with longer interval (1 to 3 years). Results: A total of 62 children met API at median age of 2.3 years. During follow-up period (median age: 11.3 years), a total of 198 wheezing episodes were observed. 81% of wheezing intervals were within 3 years from the earlier wheezing episode, including 60% within 1 year. Children who met API based on 1-year interval (n = 40) vs 1- to 3-year interval (n = 13) appeared to be similar in regard to the known risk factors for asthma. Conclusions: Our exploratory study finding suggests that children who had frequent wheezing episodes with longer interval (<3 years) need to be considered to be determined as asthma cases when API is applied to retrospective medical records. Prospective studies with a larger sample size need to replicate this finding.

KW - Asthma predictive index

KW - Heterogeneity

KW - Medical records

KW - Retrospective studies

KW - Wheezing

UR - http://www.scopus.com/inward/record.url?scp=85041562588&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85041562588&partnerID=8YFLogxK

U2 - 10.1111/all.13403

DO - 10.1111/all.13403

M3 - Article

C2 - 29319899

AN - SCOPUS:85041562588

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

SN - 0105-4538

ER -