Use of Remdesivir in Myasthenia gravis and COVID-19

Bradley J. Peters, Alejandro A. Rabinstein, Hilary M. DuBrock

Research output: Contribution to journalArticlepeer-review

Abstract

Myasthenia gravis and the associated pharmacologic management options could place patients at higher risk of contracting severe acute respiratory syndrome coronavirus 2 and exhibiting more severe manifestations of the novel coronavirus disease 2019 (COVID-19). Multiple agents have been studied for the management of the COVID-19, including remdesivir. To date, no published reports have evaluated the utilization of the antiviral remdesivir in patients with myasthenia gravis. We describe the first reported clinical course of three patients with myasthenia gravis who safely received remdesivir in combination with dexamethasone for the management of COVID-19.

Original languageEnglish (US)
Pages (from-to)546-550
Number of pages5
JournalPharmacotherapy
Volume41
Issue number6
DOIs
StatePublished - Jun 2021

Keywords

  • COVID
  • COVID-19
  • Myasthenia gravis
  • Remdesivir
  • SARS
  • coronavirus

ASJC Scopus subject areas

  • Pharmacology (medical)

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