Use of anterior temporal lobectomy for epilepsy in a community-based population

Jamie Van Gompel, Ruth Ottman, Gregory Alan Worrell, W. Richard Marsh, Nicholas M. Wetjen, Gregory D Cascino, Fredric B. Meyer

Research output: Contribution to journalArticle

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Abstract

Objective: To assess the hypothesis that use of anterior temporal lobectomy (ATL) for temporal epilepsy has diminished over time. Design: Population-based cohort study. Setting: The Rochester Epidemiology Project based in Olmsted County, Minnesota. Participants: Residents of Olmsted County. Main Outcome Measures: Poisson regression was used to evaluate changes in ATL use over time by sex. Results: Over a 17-year period, from 1993 to 2009, 847 ATLs were performed with the primary indication of epilepsy (average, 50 procedures/y). Of these, 26 occurred among Olmsted County residents. The use rates declined significantly between 1993 and 2000 (8 years) and 2001 and 2009 (9 years) according to Poisson regression analysis, from 1.9 to 0.7 per 100 000 person-years (P =.01). The rate of ATL use among Olmsted County residents was 1.2 (95% CI, 0.9 to 2.4) per 100 000 person-years of follow-up over this 17-year period. The sex-specific rates were 1.6 (95% CI, 0.9 to 2.4) and 0.7 (95% CI, 0.2 to 1.3) per 100 000 person-years for females and males, respectively. Conclusions: In this community-based cohort, the rate of ATL use was 1.2 per 100 000 person-years of follow-up. Use of this procedure has declined over time; the reasons for this are unknown but do not include referral pattern changes.

Original languageEnglish (US)
Pages (from-to)1476-1481
Number of pages6
JournalArchives of Neurology
Volume69
Issue number11
DOIs
StatePublished - Nov 2012

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Anterior Temporal Lobectomy
Epilepsy
Population
Epidemiology
Cohort Studies
Referral and Consultation
Regression Analysis
Outcome Assessment (Health Care)
Person
Residents

ASJC Scopus subject areas

  • Clinical Neurology
  • Arts and Humanities (miscellaneous)

Cite this

Use of anterior temporal lobectomy for epilepsy in a community-based population. / Van Gompel, Jamie; Ottman, Ruth; Worrell, Gregory Alan; Marsh, W. Richard; Wetjen, Nicholas M.; Cascino, Gregory D; Meyer, Fredric B.

In: Archives of Neurology, Vol. 69, No. 11, 11.2012, p. 1476-1481.

Research output: Contribution to journalArticle

Van Gompel, Jamie ; Ottman, Ruth ; Worrell, Gregory Alan ; Marsh, W. Richard ; Wetjen, Nicholas M. ; Cascino, Gregory D ; Meyer, Fredric B. / Use of anterior temporal lobectomy for epilepsy in a community-based population. In: Archives of Neurology. 2012 ; Vol. 69, No. 11. pp. 1476-1481.
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