US cost burden of ischemic stroke: A systematic literature review

Bart M Demaerschalk, Ha Mill Hwang, Grace Leung

Research output: Contribution to journalArticle

120 Citations (Scopus)

Abstract

Background: Stroke is an expensive disease from a patient, caregiver, and societal perspective. In spite of the high cost burden, only limited numbers of recent studies have focused on stroke-related costs in the United States. Objective: To conduct a systematic literature review to determine current US costs of stroke and to assess if a gap in available information exists. Methods: A literature search was conducted using the PubMed/MEDLINE and Ovid/EMBASE databases, within the date range of January 1995 to July 2008. The search, screening, application of eligibility criteria, appraisal, data extraction, and synthesis were completed by one investigator and then independently confirmed by a second. Results: The literature review revealed that the majority of cost-related analyses focused on short-term in-hospital care and early critical care as the key drivers of acute ischemic stroke hospitalization costs. Moreover, long-term medical expenses resulting from nursing home and ambulatory care as well as indirect expenditure from lost earnings and informal care represent the most significant burden on lifetime costs of stroke. Conclusions: Further studies that focus on these long-term and indirect expenditures are essential to assess the impact of new treatments on total stroke costs. Overall, the high costs associated with stroke clearly indicate there is an imperative need for effective preventive therapy, early critical care, and rehabilitation, which in turn will reduce the national expenditure for stroke-related healthcare services and improve productivity.

Original languageEnglish (US)
Pages (from-to)525-533
Number of pages9
JournalAmerican Journal of Managed Care
Volume16
Issue number7
StatePublished - Jul 2010

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Stroke
Costs and Cost Analysis
Health Expenditures
Critical Care
Home Care Services
Ambulatory Care
Nursing Care
Nursing Homes
PubMed
MEDLINE
Caregivers
Patient Care
Hospitalization
Rehabilitation
Research Personnel
Databases
Delivery of Health Care
Therapeutics

ASJC Scopus subject areas

  • Health Policy
  • Medicine(all)

Cite this

US cost burden of ischemic stroke : A systematic literature review. / Demaerschalk, Bart M; Hwang, Ha Mill; Leung, Grace.

In: American Journal of Managed Care, Vol. 16, No. 7, 07.2010, p. 525-533.

Research output: Contribution to journalArticle

Demaerschalk, Bart M ; Hwang, Ha Mill ; Leung, Grace. / US cost burden of ischemic stroke : A systematic literature review. In: American Journal of Managed Care. 2010 ; Vol. 16, No. 7. pp. 525-533.
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