Urinary BTA: Indicator of bladder cancer or of hematuria

Makito Miyake; Steve Goodison; Wasia Rizwani; Shanti Ross; H. Bart Grossman; Charles J. Rosser

doi:10.1007/s00345-012-0935-9

Urinary BTA: Indicator of bladder cancer or of hematuria

Makito Miyake, Steve Goodison, Wasia Rizwani, Shanti Ross, H. Bart Grossman, Charles J. Rosser

Quantitative Health Sciences

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Background: In this study, we investigated the influence of hematuria on the performance of the bladder tumor antigen (BTA) tests in a clinical cohort and in an experimental model. Materials and methods: Urine samples from a cohort of 126 subjects (64 with BCa and 62 controls) were analyzed by ELISA for hemoglobin and BTA. The experimental model involved the spiking of urine with blood from the same subject, and hemoglobin, red blood cell count, and BTA levels (BTA stat

Original language	English (US)
Pages (from-to)	869-873
Number of pages	5
Journal	World Journal of Urology
Volume	30
Issue number	6
DOIs	https://doi.org/10.1007/s00345-012-0935-9
State	Published - Dec 2012

Keywords

BTA
Bladder cancer
Complement factor H
Diagnosis
Hematuria

ASJC Scopus subject areas

Urology

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10.1007/s00345-012-0935-9

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title = "Urinary BTA: Indicator of bladder cancer or of hematuria",

abstract = "Background: In this study, we investigated the influence of hematuria on the performance of the bladder tumor antigen (BTA) tests in a clinical cohort and in an experimental model. Materials and methods: Urine samples from a cohort of 126 subjects (64 with BCa and 62 controls) were analyzed by ELISA for hemoglobin and BTA. The experimental model involved the spiking of urine with blood from the same subject, and hemoglobin, red blood cell count, and BTA levels (BTA stat",

keywords = "BTA, Bladder cancer, Complement factor H, Diagnosis, Hematuria",

author = "Makito Miyake and Steve Goodison and Wasia Rizwani and Shanti Ross and {Bart Grossman}, H. and Rosser, {Charles J.}",

note = "Funding Information: Acknowledgments This work was supported by the research grants from the Florida Department of Health James and Esther King Team Science Award 10KT-01 (CJR), the National Cancer Institute RO1 CA116161 (SG), and the Flight Attendant Medical Research Institute (CJR).",

year = "2012",

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doi = "10.1007/s00345-012-0935-9",

language = "English (US)",

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TY - JOUR

T1 - Urinary BTA

T2 - Indicator of bladder cancer or of hematuria

AU - Miyake, Makito

AU - Goodison, Steve

AU - Rizwani, Wasia

AU - Ross, Shanti

AU - Bart Grossman, H.

AU - Rosser, Charles J.

N1 - Funding Information: Acknowledgments This work was supported by the research grants from the Florida Department of Health James and Esther King Team Science Award 10KT-01 (CJR), the National Cancer Institute RO1 CA116161 (SG), and the Flight Attendant Medical Research Institute (CJR).

PY - 2012/12

Y1 - 2012/12

N2 - Background: In this study, we investigated the influence of hematuria on the performance of the bladder tumor antigen (BTA) tests in a clinical cohort and in an experimental model. Materials and methods: Urine samples from a cohort of 126 subjects (64 with BCa and 62 controls) were analyzed by ELISA for hemoglobin and BTA. The experimental model involved the spiking of urine with blood from the same subject, and hemoglobin, red blood cell count, and BTA levels (BTA stat

AB - Background: In this study, we investigated the influence of hematuria on the performance of the bladder tumor antigen (BTA) tests in a clinical cohort and in an experimental model. Materials and methods: Urine samples from a cohort of 126 subjects (64 with BCa and 62 controls) were analyzed by ELISA for hemoglobin and BTA. The experimental model involved the spiking of urine with blood from the same subject, and hemoglobin, red blood cell count, and BTA levels (BTA stat

KW - BTA

KW - Bladder cancer

KW - Complement factor H

KW - Diagnosis

KW - Hematuria

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Urinary BTA: Indicator of bladder cancer or of hematuria

Abstract

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