TY - JOUR
T1 - Update on Treatment of Clostridioides difficile Infection
AU - Cho, Janice M.
AU - Pardi, Darrell S.
AU - Khanna, Sahil
N1 - Publisher Copyright:
Copyright © 2019 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Clostridioides difficile infection (CDI) is the leading cause of health care-associated infections in the United States. The increasing incidence and recurrence rates of CDI together with its associated morbidity and mortality are great concerns. Newer treatment methods, such as narrow-spectrum antibiotics, monoclonal antibodies, and microbial replacement therapies, are being developed and implemented. We searched PubMed to identify published literature from 2010 to 2018 using the following keywords: Clostridium difficile, treatment, and therapy. Cited references were also used to identify relevant literature. This review focuses on the current standard of therapy and emerging therapies for CDI and summarizes the updated guidelines on treatment of CDI.
AB - Clostridioides difficile infection (CDI) is the leading cause of health care-associated infections in the United States. The increasing incidence and recurrence rates of CDI together with its associated morbidity and mortality are great concerns. Newer treatment methods, such as narrow-spectrum antibiotics, monoclonal antibodies, and microbial replacement therapies, are being developed and implemented. We searched PubMed to identify published literature from 2010 to 2018 using the following keywords: Clostridium difficile, treatment, and therapy. Cited references were also used to identify relevant literature. This review focuses on the current standard of therapy and emerging therapies for CDI and summarizes the updated guidelines on treatment of CDI.
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U2 - 10.1016/j.mayocp.2019.08.006
DO - 10.1016/j.mayocp.2019.08.006
M3 - Review article
C2 - 32247350
AN - SCOPUS:85083022612
SN - 0025-6196
VL - 95
SP - 758
EP - 769
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 4
ER -