TY - JOUR
T1 - Update on the Epidemiology of Multiple Sclerosis
AU - WYNN, DANIEL R.
AU - RODRIGUEZ, MOSES
AU - O'FALLON, W. MICHAEL
AU - KURLAND, LEONARD T.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1989
Y1 - 1989
N2 - Neuroepidemiology has been important in providing clues about the cause and pathogenesis of multiple sclerosis. In this review, we update the incidence and prevalence rates of multiple sclerosis in Olmsted County, Minnesota, and examine the potential role of viruses, exposure to animals, toxins, trauma, and diet in the development of this disease. Diseases of probable autoimmune nature have also been linked to multiple sclerosis. These descriptive data may contribute to the formulation of testable specific hypotheses about the pathogenesis and treatment of multiple sclerosis and other demyelinating diseases.
AB - Neuroepidemiology has been important in providing clues about the cause and pathogenesis of multiple sclerosis. In this review, we update the incidence and prevalence rates of multiple sclerosis in Olmsted County, Minnesota, and examine the potential role of viruses, exposure to animals, toxins, trauma, and diet in the development of this disease. Diseases of probable autoimmune nature have also been linked to multiple sclerosis. These descriptive data may contribute to the formulation of testable specific hypotheses about the pathogenesis and treatment of multiple sclerosis and other demyelinating diseases.
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U2 - 10.1016/S0025-6196(12)61754-6
DO - 10.1016/S0025-6196(12)61754-6
M3 - Article
C2 - 2671520
AN - SCOPUS:0024453006
SN - 0025-6196
VL - 64
SP - 808
EP - 817
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 7
ER -