Update in Intracerebral Hemorrhage

Maria I. Aguilar, Thomas G Brott

Research output: Contribution to journalReview article

39 Citations (Scopus)

Abstract

Spontaneous, nontraumatic intracerebral hemorrhage (ICH) is defined as bleeding within the brain parenchyma. Intracranial hemorrhage includes bleeding within the cranial vault and encompasses ICH, subdural hematoma, epidural bleeds, and subarachnoid hemorrhage (SAH). This review will focus only on ICH. This stroke subtype accounts for about 10% of all strokes. The hematoma locations are deep or ganglionic, lobar, cerebellar, and brain stem in descending order of frequency. Intracerebral hemorrhage occurs twice as common as SAH and is equally as deadly. Risk factors for ICH include hypertension, cerebral amyloid angiopathy, advanced age, antithrombotic therapy and history of cerebrovascular disease. The clinical presentation is “stroke like” with sudden onset of focal neurological deficits. Noncontrast head computerized tomography (CT) scan is the standard diagnostic tool. However, newer neuroimaging techniques have improved the diagnostic yield in terms of underlying pathophysiology and may aid in prognosis. Intracerebral hemorrhage is a neurological emergency. Medical care begins with stabilization of airway, breathing function, and circulation (ABCs), followed by specific measures aimed to decrease secondary neurological damage and to prevent both medical and neurological complications. Reversal of coagulopathy when present is of the essence. Blood pressure management can be key and continues as an area of debate and ongoing research. Surgical evacuation of ICH is of unproven benefit though a subset of well-selected patients may have improved outcomes. Ventriculostomy and intracranial pressure (ICP) monitoring are interventions also used in this patient population. To date, hemostatic medications and neuroprotectants have failed to result in clinical improvement. A multidisciplinary approach is recommended, with participation of vascular neurology, vascular neurosurgery, critical care, and rehabilitation medicine as the main players.

Original languageEnglish (US)
Pages (from-to)148-159
Number of pages12
JournalThe Neurohospitalist
Volume1
Issue number3
DOIs
StatePublished - 2011

Fingerprint

Cerebral Hemorrhage
Stroke
Subarachnoid Hemorrhage
Blood Vessels
Cerebral Amyloid Angiopathy
Ventriculostomy
Hemorrhage
Cerebrovascular Disorders
Subdural Hematoma
Intracranial Hemorrhages
Intracranial Pressure
Neurosurgery
Neuroprotective Agents
Hemostatics
Critical Care
Neurology
Neuroimaging
Hematoma
Brain Stem
Respiration

Keywords

  • diagnosis
  • intracerebral hemorrhage
  • prognosis
  • surgery
  • treatment

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Update in Intracerebral Hemorrhage. / Aguilar, Maria I.; Brott, Thomas G.

In: The Neurohospitalist, Vol. 1, No. 3, 2011, p. 148-159.

Research output: Contribution to journalReview article

Aguilar, Maria I. ; Brott, Thomas G. / Update in Intracerebral Hemorrhage. In: The Neurohospitalist. 2011 ; Vol. 1, No. 3. pp. 148-159.
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