TY - JOUR
T1 - Unusual compulsive behaviors primarily related to dopamine agonist therapy in Parkinson's disease and multiple system atrophy
AU - McKeon, Andrew
AU - Josephs, Keith A.
AU - Klos, Kevin J.
AU - Hecksel, Kathleen
AU - Bower, James H.
AU - Michael Bostwick, J.
AU - Eric Ahlskog, J.
PY - 2007/12
Y1 - 2007/12
N2 - Unusual compulsive behaviors (weighing, card and video game playing, fishing, gardening, intense interest in established hobbies, locking and unlocking doors, repetitive dressing and undressing) occurred in relation to dopamine agonist therapy (six patients) and levodopa therapy (one patient) in seven patients with parkinsonism (seven Parkinson's disease, one multiple system atrophy). These behaviors occurred in tandem with pathological gambling, hypersexuality, compulsive eating, compulsive shopping or punding in six of the seven cases. Obsessive thoughts were present in one patient, with no prior history of obsessive-compulsive disorder. The simultaneous occurrence of these phenomenologically distinct behaviors in this group of patients suggests that a broad spectrum of psychopathology may occur in this context and should be monitored for in routine neurological practice.
AB - Unusual compulsive behaviors (weighing, card and video game playing, fishing, gardening, intense interest in established hobbies, locking and unlocking doors, repetitive dressing and undressing) occurred in relation to dopamine agonist therapy (six patients) and levodopa therapy (one patient) in seven patients with parkinsonism (seven Parkinson's disease, one multiple system atrophy). These behaviors occurred in tandem with pathological gambling, hypersexuality, compulsive eating, compulsive shopping or punding in six of the seven cases. Obsessive thoughts were present in one patient, with no prior history of obsessive-compulsive disorder. The simultaneous occurrence of these phenomenologically distinct behaviors in this group of patients suggests that a broad spectrum of psychopathology may occur in this context and should be monitored for in routine neurological practice.
KW - Compulsions
KW - Dopamine agonists
UR - http://www.scopus.com/inward/record.url?scp=36048948590&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36048948590&partnerID=8YFLogxK
U2 - 10.1016/j.parkreldis.2007.04.004
DO - 10.1016/j.parkreldis.2007.04.004
M3 - Article
C2 - 17544807
AN - SCOPUS:36048948590
SN - 1353-8020
VL - 13
SP - 516
EP - 519
JO - Parkinsonism and Related Disorders
JF - Parkinsonism and Related Disorders
IS - 8
ER -