Unintegrated Lentivirus DNA Persistence and Accessibility to Expression in Nondividing Cells: Analysis with Class I Integrase Mutants

Agriculture & Biology

• Lentivirus 100%
• integrases 95%
• Feline immunodeficiency virus 68%
• mutants 41%
• DNA 36%
• Human immunodeficiency virus 1 32%
• transgenes 25%
• cells 22%
• neurons 22%
• RNA-directed DNA polymerase 21%
• cell cycle 15%
• fibroblasts 15%
• terminal repeat sequences 10%
• rats 9%
• retina 8%
• Southern blotting 8%
• cell division 7%
• cell growth 7%
• protein synthesis 6%
• transcription (genetics) 6%
• mutation 6%
• monitoring 5%
• infection 4%
• testing 3%

Medicine & Life Sciences

• Integrases 93%
• Lentivirus 84%
• Feline Immunodeficiency Virus 72%
• DNA 39%
• Transgenes 30%
• RNA-Directed DNA Polymerase 23%
• HIV-1 17%
• Cell Cycle 16%
• p31 integrase protein, Human immunodeficiency virus 1 15%
• Fibroblasts 15%
• Aphidicolin 14%
• Retinal Neurons 13%
• Terminal Repeat Sequences 12%
• Retinal Ganglion Cells 11%
• Southern Blotting 11%
• Growth 10%
• Cell Division 9%
• Retina 8%
• Complementary DNA 8%
• HIV 7%
• Neurons 6%
• Polymerase Chain Reaction 6%
• Mutation 5%
• Infections 4%
• Proteins 3%