TY - JOUR
T1 - Uncommon variants of mature T-cell lymphomas (MTCLs)
T2 - Imaging and histopathologic and clinical features with updates from the fourth edition of the world health organization (WHO) classification of lymphoid neoplasms
AU - Salem, Ahmed Ebada
AU - Zaki, Yehia H.
AU - El-Hussieny, Gamal
AU - ElNoueam, Khaled I.
AU - Shaaban, Akram M.
AU - Koppula, Bhasker Rao
AU - Yang, Ming
AU - Salama, Mohamed
AU - Elsayes, Khaled M.
AU - Covington, Matthew F.
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/10/1
Y1 - 2021/10/1
N2 - Understanding the pathogenesis and molecular biology of malignant lymphomas is challenging, given the complex nature and incongruity of these disorders. The classification of lymphoma is continually evolving to account for advances in clinical, pathological, molecular biology and cytogenetic aspects, which impact our understanding of these disorders. The latest fourth edition of the WHO classification of lymphoid malignancies was released in 2016 to account for these changes. Additionally, unlike B-cell lymphomas (BCL), T-cell lymphomas (TCL) are uncommon, and may be sporadically experienced in clinical practice. These disorders are rare, thus early diagnosis is challenging for both physicians and radiologists, owing to the overlap in clinical and imaging features with other, more common disorders. We aim to discuss some rare variants of T-cell lymphomas, including clinicopathologic and imaging features, as well as to give a glimpse of the updates contained within the new 2016 WHO classification.
AB - Understanding the pathogenesis and molecular biology of malignant lymphomas is challenging, given the complex nature and incongruity of these disorders. The classification of lymphoma is continually evolving to account for advances in clinical, pathological, molecular biology and cytogenetic aspects, which impact our understanding of these disorders. The latest fourth edition of the WHO classification of lymphoid malignancies was released in 2016 to account for these changes. Additionally, unlike B-cell lymphomas (BCL), T-cell lymphomas (TCL) are uncommon, and may be sporadically experienced in clinical practice. These disorders are rare, thus early diagnosis is challenging for both physicians and radiologists, owing to the overlap in clinical and imaging features with other, more common disorders. We aim to discuss some rare variants of T-cell lymphomas, including clinicopathologic and imaging features, as well as to give a glimpse of the updates contained within the new 2016 WHO classification.
KW - 2016 WHO classification of hematologic malignancies
KW - FDG-PET/CT
KW - Imaging
KW - Mature-T-cell lymphoma
KW - Updates
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U2 - 10.3390/cancers13205217
DO - 10.3390/cancers13205217
M3 - Article
AN - SCOPUS:85117712624
SN - 2072-6694
VL - 13
JO - Cancers
JF - Cancers
IS - 20
M1 - 5217
ER -