Ultrasound tomography imaging with waveform sound speed: Parenchymal changes in women undergoing tamoxifen therapy

Mark Sak, Neb Duric, Peter Littrup, Mark Sherman, Gretchen Gierach

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Ultrasound tomography (UST) is an emerging modality that can offer quantitative measurements of breast density. Recent breakthroughs in UST image reconstruction involve the use of a waveform reconstruction as opposed to a raybased reconstruction. The sound speed (SS) images that are created using the waveform reconstruction have a much higher image quality. These waveform images offer improved resolution and contrasts between regions of dense and fatty tissues. As part of a study that was designed to assess breast density changes using UST sound speed imaging among women undergoing tamoxifen therapy, UST waveform sound speed images were then reconstructed for a subset of participants. These initial results show that changes to the parenchymal tissue can more clearly be visualized when using the waveform sound speed images. Additional quantitative testing of the waveform images was also started to test the hypothesis that waveform sound speed images are a more robust measure of breast density than ray-based reconstructions. Further analysis is still needed to better understand how tamoxifen affects breast tissue.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2017
Subtitle of host publicationUltrasonic Imaging and Tomography
EditorsNeb Duric, Neb Duric, Brecht Heyde
PublisherSPIE
ISBN (Electronic)9781510607231
DOIs
StatePublished - 2017
EventMedical Imaging 2017: Ultrasonic Imaging and Tomography - Orlando, United States
Duration: Feb 15 2017Feb 16 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10139
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2017: Ultrasonic Imaging and Tomography
CountryUnited States
CityOrlando
Period2/15/172/16/17

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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