Ultrasound surface wave elastography of the living human eye

Xiaoming Zhang, Jay McLaren, Arash Kazemi, Shuai Chun Lin, Christopher M. Pruet, Arthur J Sit

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The purpose of this paper was to demonstrate a noninvasive technique to measure elastic properties of human eyes using ultrasound surface wave elastography (USWE) technique. Twenty eyes of 10 healthy subjects (age 44-63; mean 51 years) were studied. A localized harmonic vibration for 0.1 second at 100 Hz was generated by using a spherically-tipped vibrator (3 mm diameter) placed on the closed eyelid. The subjects only felt a gentle vibration on their eyes. The wave propagation in the eye was measured by using a linear array ultrasound transducer. The wave speed was determined from the change in phase with distance. Mean wave speed in the cornea was 1.82 ± 0.10 m/s (± SD) at 100 Hz. Intraocular pressure (IOP) was measured by using Goldmann applanation tonometry. Mean IOP was 12.8 ± 2.7 mmHg (± SD). The wave speed correlated well with IOP (r=0.74; p<0.001). USWE is a safe and noninvasive technique for generating and measuring wave propagation in the eye. Further improvement and validation of USWE in the eye experiments is needed.

Original languageEnglish (US)
Title of host publication2016 IEEE International Ultrasonics Symposium, IUS 2016
PublisherIEEE Computer Society
Volume2016-November
ISBN (Electronic)9781467398978
DOIs
StatePublished - Nov 1 2016
Event2016 IEEE International Ultrasonics Symposium, IUS 2016 - Tours, France
Duration: Sep 18 2016Sep 21 2016

Other

Other2016 IEEE International Ultrasonics Symposium, IUS 2016
CountryFrance
CityTours
Period9/18/169/21/16

Fingerprint

surface waves
intraocular pressure
tonometry
wave propagation
vibration
cornea
linear arrays
transducers
elastic properties
harmonics

Keywords

  • cornea
  • eye
  • surface wave elastography
  • ultrasound

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Zhang, X., McLaren, J., Kazemi, A., Lin, S. C., Pruet, C. M., & Sit, A. J. (2016). Ultrasound surface wave elastography of the living human eye. In 2016 IEEE International Ultrasonics Symposium, IUS 2016 (Vol. 2016-November). [7728510] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2016.7728510

Ultrasound surface wave elastography of the living human eye. / Zhang, Xiaoming; McLaren, Jay; Kazemi, Arash; Lin, Shuai Chun; Pruet, Christopher M.; Sit, Arthur J.

2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November IEEE Computer Society, 2016. 7728510.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zhang, X, McLaren, J, Kazemi, A, Lin, SC, Pruet, CM & Sit, AJ 2016, Ultrasound surface wave elastography of the living human eye. in 2016 IEEE International Ultrasonics Symposium, IUS 2016. vol. 2016-November, 7728510, IEEE Computer Society, 2016 IEEE International Ultrasonics Symposium, IUS 2016, Tours, France, 9/18/16. https://doi.org/10.1109/ULTSYM.2016.7728510
Zhang X, McLaren J, Kazemi A, Lin SC, Pruet CM, Sit AJ. Ultrasound surface wave elastography of the living human eye. In 2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November. IEEE Computer Society. 2016. 7728510 https://doi.org/10.1109/ULTSYM.2016.7728510
Zhang, Xiaoming ; McLaren, Jay ; Kazemi, Arash ; Lin, Shuai Chun ; Pruet, Christopher M. ; Sit, Arthur J. / Ultrasound surface wave elastography of the living human eye. 2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November IEEE Computer Society, 2016.
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