Ultrasound-stimulated vibro-acoustic imaging in vivo

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations

Abstract

The time dependent radiation force produced by modulating an ultrasonic beam can be used to excite mechanical waves in an insonified object. The amplitude and phase of the resulting acoustic emission can be measured with a sensitive hydrophone, and are dependent on the reflectivity and stiffness of the insonified region. To test the hypothesis that this method would provide images of biologic materials, we scanned a pig artery. A spherically focused, 3.0 MHz, 45 mm diameter transducer with a central disc and a surrounding annulus was raster scanned over the subject. The disc and annulus were separately driven by rf signals separated in frequency by approximately 35 kHz. Interference of the two beams at the focal point, produced cyclic displacement of excised and in vivo arteries at the difference frequency. Recording the amplitude and phase of the emitted sound resulted in images showing arteries with very little speckle. The method appears to be sensitive to sub-nanometers of mechanical displacement.

Original languageEnglish (US)
Pages (from-to)1635-1638
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume2
StatePublished - Dec 1 1998
EventProceedings of the 1998 International Ultrasonics Symposium - Sendai, Miyagi, Jpn
Duration: Oct 5 1998Oct 8 1998

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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