Abstract
Introduction: Changes in subsynovial connective tissue (SSCT) in carpal tunnel syndrome (CTS) patients may result in altered dynamics; consequently, quantification of these dynamics might support objective diagnosis of CTS. Methods: We measured and compared longitudinal excursion of the flexor digitorum superficialis and profundus tendons, the median nerve, and the SSCT between the most and least affected hands of 51 CTS patients during extension-to-fist motion. Results: Median nerve and flexor digitorum superficialis tendon excursions in the most affected hands were smaller than in the least affected hands of the same patients, whereas the excursions of the flexor digitorum profundus were larger. Based on these excursions, logistic regression models classified between 67% and 86% of the hands correctly as having CTS. Conclusions: The altered hand dynamics in CTS patients may have implications for the pathophysiology and clinical evaluation of CTS, and ultrasound-based classification models may further support the diagnosis of CTS.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 721-729 |
| Number of pages | 9 |
| Journal | Muscle and Nerve |
| Volume | 45 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2012 |
Fingerprint
Keywords
- Carpal tunnel syndrome
- Diagnostic tool
- Hand dynamics
- Subsynovial connective tissue
- Ultrasound
ASJC Scopus subject areas
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Physiology (medical)
- Physiology
Cite this
Ultrasonographic assessment of longitudinal median nerve and hand flexor tendon dynamics in carpal tunnel syndrome. / Korstanje, Jan Wiebe H; Boer, Marjan Scheltens De; Blok, Joleen H.; Amadio, Peter C; Hovius, Steven E R; Stam, Henk J.; Selles, Ruud W.
In: Muscle and Nerve, Vol. 45, No. 5, 05.2012, p. 721-729.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ultrasonographic assessment of longitudinal median nerve and hand flexor tendon dynamics in carpal tunnel syndrome
AU - Korstanje, Jan Wiebe H
AU - Boer, Marjan Scheltens De
AU - Blok, Joleen H.
AU - Amadio, Peter C
AU - Hovius, Steven E R
AU - Stam, Henk J.
AU - Selles, Ruud W.
PY - 2012/5
Y1 - 2012/5
N2 - Introduction: Changes in subsynovial connective tissue (SSCT) in carpal tunnel syndrome (CTS) patients may result in altered dynamics; consequently, quantification of these dynamics might support objective diagnosis of CTS. Methods: We measured and compared longitudinal excursion of the flexor digitorum superficialis and profundus tendons, the median nerve, and the SSCT between the most and least affected hands of 51 CTS patients during extension-to-fist motion. Results: Median nerve and flexor digitorum superficialis tendon excursions in the most affected hands were smaller than in the least affected hands of the same patients, whereas the excursions of the flexor digitorum profundus were larger. Based on these excursions, logistic regression models classified between 67% and 86% of the hands correctly as having CTS. Conclusions: The altered hand dynamics in CTS patients may have implications for the pathophysiology and clinical evaluation of CTS, and ultrasound-based classification models may further support the diagnosis of CTS.
AB - Introduction: Changes in subsynovial connective tissue (SSCT) in carpal tunnel syndrome (CTS) patients may result in altered dynamics; consequently, quantification of these dynamics might support objective diagnosis of CTS. Methods: We measured and compared longitudinal excursion of the flexor digitorum superficialis and profundus tendons, the median nerve, and the SSCT between the most and least affected hands of 51 CTS patients during extension-to-fist motion. Results: Median nerve and flexor digitorum superficialis tendon excursions in the most affected hands were smaller than in the least affected hands of the same patients, whereas the excursions of the flexor digitorum profundus were larger. Based on these excursions, logistic regression models classified between 67% and 86% of the hands correctly as having CTS. Conclusions: The altered hand dynamics in CTS patients may have implications for the pathophysiology and clinical evaluation of CTS, and ultrasound-based classification models may further support the diagnosis of CTS.
KW - Carpal tunnel syndrome
KW - Diagnostic tool
KW - Hand dynamics
KW - Subsynovial connective tissue
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=84859773771&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859773771&partnerID=8YFLogxK
U2 - 10.1002/mus.23246
DO - 10.1002/mus.23246
M3 - Article
C2 - 22499100
AN - SCOPUS:84859773771
VL - 45
SP - 721
EP - 729
JO - Muscle and Nerve
JF - Muscle and Nerve
SN - 0148-639X
IS - 5
ER -