Type 2 Diabetes Mellitus and Heart Failure, A Scientific Statement From the American Heart Association and Heart Failure Society of America

Heart Failure Society of America, American Heart Association Heart Failure and Transplantation Committee of the Council on Clinical Cardiology, Council on Cardiovascular and Stroke Nursing

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Type 2 diabetes mellitus is a risk factor for incident heart failure and increases the risk of morbidity and mortality in patients with established disease. Secular trends in the prevalence of diabetes mellitus and heart failure forecast a growing burden of disease and underscore the need for effective therapeutic strategies. Recent clinical trials have demonstrated the shared pathophysiology between diabetes mellitus and heart failure, the synergistic effect of managing both conditions, and the potential for diabetes mellitus therapies to modulate the risk of heart failure outcomes. This scientific statement on diabetes mellitus and heart failure summarizes the epidemiology, pathophysiology, and impact of diabetes mellitus and its control on outcomes in heart failure; reviews the approach to pharmacological therapy and lifestyle modification in patients with diabetes mellitus and heart failure; highlights the value of multidisciplinary interventions to improve clinical outcomes in this population; and outlines priorities for future research.

Original languageEnglish (US)
Pages (from-to)584-619
Number of pages36
JournalJournal of Cardiac Failure
Volume25
Issue number8
DOIs
StatePublished - Aug 2019

Keywords

  • AHA Scientific Statement
  • Diabetes mellitus, type 2
  • Drug therapy
  • Heart failure
  • Lifestyle
  • Risk factors

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Heart Failure Society of America, American Heart Association Heart Failure and Transplantation Committee of the Council on Clinical Cardiology, & Council on Cardiovascular and Stroke Nursing (2019). Type 2 Diabetes Mellitus and Heart Failure, A Scientific Statement From the American Heart Association and Heart Failure Society of America. Journal of Cardiac Failure, 25(8), 584-619. https://doi.org/10.1016/j.cardfail.2019.05.007