Twelve-month outcomes of excisional goniotomy using the kahook dual blade in eyes with angleclosure glaucoma

Syril Dorairaj, Mai Dang Tam, Goundappa K. Balasubramani

Research output: Contribution to journalArticle

Abstract

Purpose: To characterize clinical outcomes following Kahook Dual Blade (KDB)-assisted goniosynechialysis and excisional goniotomy combined with phacoemulsification in eyes with angle-closure glaucoma and cataract. Setting: Two clinical practices. Methods: In this retrospective analysis of existing health records, data were collected from 42 eyes of 24 subjects from preoperative, operative, and postoperative encounters through 12 months of follow-up. Outcomes included changes in mean IOP, IOP-lowering medications, and logMAR best-corrected visual acuity (BCVA), as well as the proportions of patients achieving IOP reductions =20%, IOP =18 mmHg, and a reduction of =1 medication. Results: Preoperative, mean (standard error) IOP was 25.5 (0.7) mmHg and at Month 12 was reduced by 12.3 (0.73) mmHg (-47.2%; p<0.0001). The mean number of IOP-lowering medications used was 2.3 (0.1) preoperatively and was reduced at Month 12 by 2.2 (0.12) (-91.7%; p<0.0001). At Month 12, 92.9% of eyes achieved IOP =18 mmHg, 100% achieved IOP reduction of =20%, 95.2% required =1 fewer medications for IOP control, and 85.7% (36/42) were medication-free. Mean LogMAR BCVA improved from 0.547 (0.06) at baseline to 0.159 (0.07) at Month 12. Conclusion: KDB-assisted goniosynechialysis and excisional goniotomy at the time of phacoemulsification safely provide significant reductions in both IOP and IOP-lowering medication burden in eyes with angle-closure glaucoma, while simultaneously improving visual acuity.

Original languageEnglish (US)
Pages (from-to)1779-1785
Number of pages7
JournalClinical Ophthalmology
Volume13
DOIs
StatePublished - Jan 1 2019

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Trabeculectomy
Glaucoma
Visual Acuity
Angle Closure Glaucoma
Phacoemulsification
Cataract
Health

Keywords

  • Angle closure
  • Glaucoma
  • Goniotomy
  • MIGS
  • Synechialysis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Twelve-month outcomes of excisional goniotomy using the kahook dual blade in eyes with angleclosure glaucoma. / Dorairaj, Syril; Tam, Mai Dang; Balasubramani, Goundappa K.

In: Clinical Ophthalmology, Vol. 13, 01.01.2019, p. 1779-1785.

Research output: Contribution to journalArticle

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abstract = "Purpose: To characterize clinical outcomes following Kahook Dual Blade (KDB)-assisted goniosynechialysis and excisional goniotomy combined with phacoemulsification in eyes with angle-closure glaucoma and cataract. Setting: Two clinical practices. Methods: In this retrospective analysis of existing health records, data were collected from 42 eyes of 24 subjects from preoperative, operative, and postoperative encounters through 12 months of follow-up. Outcomes included changes in mean IOP, IOP-lowering medications, and logMAR best-corrected visual acuity (BCVA), as well as the proportions of patients achieving IOP reductions =20{\%}, IOP =18 mmHg, and a reduction of =1 medication. Results: Preoperative, mean (standard error) IOP was 25.5 (0.7) mmHg and at Month 12 was reduced by 12.3 (0.73) mmHg (-47.2{\%}; p<0.0001). The mean number of IOP-lowering medications used was 2.3 (0.1) preoperatively and was reduced at Month 12 by 2.2 (0.12) (-91.7{\%}; p<0.0001). At Month 12, 92.9{\%} of eyes achieved IOP =18 mmHg, 100{\%} achieved IOP reduction of =20{\%}, 95.2{\%} required =1 fewer medications for IOP control, and 85.7{\%} (36/42) were medication-free. Mean LogMAR BCVA improved from 0.547 (0.06) at baseline to 0.159 (0.07) at Month 12. Conclusion: KDB-assisted goniosynechialysis and excisional goniotomy at the time of phacoemulsification safely provide significant reductions in both IOP and IOP-lowering medication burden in eyes with angle-closure glaucoma, while simultaneously improving visual acuity.",
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AB - Purpose: To characterize clinical outcomes following Kahook Dual Blade (KDB)-assisted goniosynechialysis and excisional goniotomy combined with phacoemulsification in eyes with angle-closure glaucoma and cataract. Setting: Two clinical practices. Methods: In this retrospective analysis of existing health records, data were collected from 42 eyes of 24 subjects from preoperative, operative, and postoperative encounters through 12 months of follow-up. Outcomes included changes in mean IOP, IOP-lowering medications, and logMAR best-corrected visual acuity (BCVA), as well as the proportions of patients achieving IOP reductions =20%, IOP =18 mmHg, and a reduction of =1 medication. Results: Preoperative, mean (standard error) IOP was 25.5 (0.7) mmHg and at Month 12 was reduced by 12.3 (0.73) mmHg (-47.2%; p<0.0001). The mean number of IOP-lowering medications used was 2.3 (0.1) preoperatively and was reduced at Month 12 by 2.2 (0.12) (-91.7%; p<0.0001). At Month 12, 92.9% of eyes achieved IOP =18 mmHg, 100% achieved IOP reduction of =20%, 95.2% required =1 fewer medications for IOP control, and 85.7% (36/42) were medication-free. Mean LogMAR BCVA improved from 0.547 (0.06) at baseline to 0.159 (0.07) at Month 12. Conclusion: KDB-assisted goniosynechialysis and excisional goniotomy at the time of phacoemulsification safely provide significant reductions in both IOP and IOP-lowering medication burden in eyes with angle-closure glaucoma, while simultaneously improving visual acuity.

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KW - MIGS

KW - Synechialysis

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