Turkey versus guinea pig red blood cells: Hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1

Inna G. Ovsyannikova; Sarah J. White; Randy A. Albrecht; Adolfo García-Sastre; Gregory A. Poland

doi:10.1089/vim.2013.0111

Turkey versus guinea pig red blood cells: Hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1

Inna G. Ovsyannikova, Sarah J. White, Randy A. Albrecht, Adolfo García-Sastre, Gregory A. Poland

General Internal Medicine

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

For influenza hemagglutination inhibition (HAI) assays, species selection of red blood cells (RBCs) is critical to determine antibody titers to influenza viruses reliably. We compared pandemic influenza virus A/H1N1 (pdH1N1) HAI titers using turkey or guinea pig RBCs. Turkey RBCs appear to be the more appropriate species choice for influenza A/pH1N1 HAI assays.

Original language	English (US)
Pages (from-to)	174-178
Number of pages	5
Journal	Viral Immunology
Volume	27
Issue number	4
DOIs	https://doi.org/10.1089/vim.2013.0111
State	Published - May 1 2014

ASJC Scopus subject areas

Immunology
Molecular Medicine
Virology

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10.1089/vim.2013.0111

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abstract = "For influenza hemagglutination inhibition (HAI) assays, species selection of red blood cells (RBCs) is critical to determine antibody titers to influenza viruses reliably. We compared pandemic influenza virus A/H1N1 (pdH1N1) HAI titers using turkey or guinea pig RBCs. Turkey RBCs appear to be the more appropriate species choice for influenza A/pH1N1 HAI assays.",

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AU - García-Sastre, Adolfo

AU - Poland, Gregory A.

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Turkey versus guinea pig red blood cells: Hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1

Abstract

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