Tumor Seeding after Robot-Assisted Radical Prostatectomy: Literature Review and Experience from a Single Institution

Giovanni Motterle, Mohamed E. Ahmed, Jack R. Andrews, Marco Moschini, Eugene D. Kwon, R. Jeffrey Karnes

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

PURPOSE: Seeding of tumor cells is a rare complication of minimally invasive surgery. We reviewed and improved current knowledge of prostate cancer seeding. MATERIALS AND METHODS: A literature review was performed using MEDLINE®, Embase® and the Cochrane Library, including cases of peritoneal and port site seeding reported after minimally invasive prostatectomy. In addition, after institutionally approved chart review a descriptive summary of a single institution experience on the topic is provided. RESULTS: The data from 9 reported cases of port site metastases from prostate cancer in the world literature are summarized along with 3 additional cases from our experience. Similarly, 5 cases of peritoneal seeding are reviewed from the literature with the addition of 3 more cases from our institution. Good long-term outcomes are achievable with multimodality and individualized regimens, including seeding directed treatments. CONCLUSIONS: Although no definitive recommendation can be made for treatment strategies for these patients, there is a need for awareness and further discussion of this atypical presentation.

Original languageEnglish (US)
Pages (from-to)1141-1146
Number of pages6
JournalThe Journal of urology
Volume203
Issue number6
DOIs
StatePublished - Jun 1 2020

Keywords

  • minimally invasive surgical procedures
  • neoplasm seeding
  • prostatectomy
  • prostatic neoplasms
  • robotic surgical procedures

ASJC Scopus subject areas

  • Urology

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