Tumefactive Multiple Sclerosis Masquerading as High Grade Glioma

Michelle Lin, Patrick Reid, Joshua Bakhsheshian

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Tumefactive multiple sclerosis is a demyelinating lesion that can radiographically mimic high-grade gliomas during acute episodes, thus affecting clinical decision making. A delay in appropriate diagnoses can result in unnecessary invasive resections. The following case is a patient with unilateral weakness and radiologic findings that were concerning for a high-grade glioma. Peripheral studies were equivocal. The decision was made to proceed with a stereotactic biopsy, yielding a definitive diagnosis of tumefactive demyelinating lesion (TDL). The patient responded robustly to medical management and made a full clinical recovery. While TDLs and gliomas may look radiologically identical during acute demyelinating episodes, unlike gliomas, TDLs will demonstrate evolvement over serial imaging and robust clinical response to high dose steroids. Clinicians should proceed with caution when considering invasive procedures with such lesions. Conservative medical management is often sufficient as seen in this patient. This case highlights the importance of timely diagnosis and management of TDLs.

Original languageEnglish (US)
Pages (from-to)37-38
Number of pages2
JournalWorld neurosurgery
Volume112
DOIs
StatePublished - Apr 2018

Keywords

  • Autoimmune
  • Demyelination
  • Glioma
  • Neurology
  • Neurosurgery
  • Oncology
  • Pseudotumor

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Tumefactive Multiple Sclerosis Masquerading as High Grade Glioma'. Together they form a unique fingerprint.

Cite this