Tumefactive cysts: A delayed complication following radiosurgery for cerebral arterial venous malformations

Whitney B. Edmister, John I. Lane, Julie R. Gilbertson, Robert D. Brown, Bruce E. Pollock

Research output: Contribution to journalArticle

13 Scopus citations


We report five cases of symptomatic delayed cyst formation after radiosurgery for intracranial arterial venous malformations. Median time to discovery of the cysts following most recent radiosurgery was 59 months (range, 34-89 months). In all five patients, the radiation therapy-induced cysts exhibited tumefactive characteristics, including vasogenic edema, mass effect, and nodular enhancement. Despite these malignant features, these cystic lesions should be recognized as a benign complication of radiosurgery so that proper treatment (i.e., cystoperitoneal shunt surgery or excision) can be initiated.

Original languageEnglish (US)
Pages (from-to)1152-1157
Number of pages6
JournalAmerican Journal of Neuroradiology
Issue number5
StatePublished - Dec 1 2005


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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