Trisomy 9 in hematologic disorders: Possible association with primary thrombocytosis

Denis Cournoyer, Pierre Noël, Michael A. Schmidt, Gordon W. Dewald

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Ten patients with a hematologic disorder and a clone of cells with trisomy 9 in the bone marrow were studied in order to investigate the clinical significance of this chromosome anomaly. In five of the patients, trisomy 9 was the only anomaly; in four, there was also trisomy 8; and in one, a Y chromosome was also lacking. Four patients had a myelodysplastic syndrome, and six had a myeloproliferative disorder. Interestingly, four patients had primary thrombocytosis.

Original languageEnglish (US)
Pages (from-to)73-78
Number of pages6
JournalCancer Genetics and Cytogenetics
Volume27
Issue number1
DOIs
StatePublished - Jul 1987

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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