Trident sign trumps Aquaporin-4-IgG ELISA in diagnostic value in a case of longitudinally extensive transverse myelitis

Evan A. Jolliffe, B Mark Keegan, Eoin Flanagan

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Longitudinally-extensive T2-hyperintense spinal cord lesions (≥3 vertebral segments) are associated with neuromyelitis optical spectrum disorder but occur with other disorders including spinal cord sarcoidosis. When linear dorsal subpial enhancement is accompanied by central cord/canal enhancement the axial post-gadolinium sequences may reveal a “trident” pattern that has previously been shown to be strongly suggestive of spinal cord sarcoidosis. We report a case in which the patient was initially diagnosed with neuromyelitis optical spectrum disorder, but where the “trident” sign ultimately led to the correct diagnosis of spinal cord sarcoidosis.

Original languageEnglish (US)
Pages (from-to)7-8
Number of pages2
JournalMultiple Sclerosis and Related Disorders
Volume23
DOIs
StatePublished - Jul 1 2018

Keywords

  • Neuromyelitis optica
  • Neuromyelitis optica spectrum disorder
  • Neurosarcoidosis
  • Sarcoidosis
  • Transverse myelitis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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