Trends in the utilization of non-steroidal anti-inflammatory drugs in the United States, 1986-1990

Sherine E. Gabriel, Richard A. Fehring

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

National estimates of NSAID utilization were obtained from two databases available from IMS America. These data illustrate that in contrast to the rapid rise in NSAID prescriptions from 1973 (27.5 million) to 1983 (66.7 million), NSAID prescriptions have recently been remarkably stable. Over the same time period, a 46 fold increase in the use of gastro-protective and/or anti-ulcer drugs concomitantly with NSAID was demonstrated. It is hypothesized that the stabilization of NSAID prescription usage coupled with the dramatic increase in usage of concomitant anti-ulcer and gastroprotective agents has occurred due to physician awareness of the increased relative risk for adverse gastrointestinal events among NSAID users compared to non-users.

Original languageEnglish (US)
Pages (from-to)1041-1044
Number of pages4
JournalJournal of Clinical Epidemiology
Volume45
Issue number9
DOIs
StatePublished - Sep 1992

Keywords

  • Non-steroidal anti-inflammatory drugs (NSAID)
  • Trends
  • Utilization

ASJC Scopus subject areas

  • Epidemiology

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