Trends in the incidence of invasive and in situ vulvar carcinoma

Patricia L. Judson, Elizabeth B Habermann, Nancy N. Baxter, Sara B. Durham, Beth A. Virnig

Research output: Contribution to journalArticle

293 Citations (Scopus)

Abstract

OBJECTIVE: To characterize the incidence of vulvar carcinoma in situ and vulvar cancer over time. METHODS: We used the Surveillance Epidemiology and End Results database to assess trends in the incidence of vulvar cancer over a 28-year period (1973 through 2000) and determined whether there had been a change in incidence over time. Information collected included patient characteristics, primary tumor site, tumor grade, and follow-up for vital status. We calculated the incidence rates by decade of age, used χ2 tests to compare demographic characteristics, and tested for trends in incidence over time. RESULTS: A total of 13,176 in situ and invasive vulvar carcinomas were identified; 57% of the women were diagnosed with in situ, 44% with invasive disease. Vulvar carcinoma in situ increased 411% from 1973 to 2000. Invasive vulvar cancer increased 20% during the same period. The incidence rates for in situ and invasive vulvar carcinomas are distributed differently across the age groups. In situ carcinoma incidence increases until the age of 40-49 years and then decreases, whereas invasive vulvar cancer risk increases as a woman ages, increasing more quickly after 50 years of age. CONCLUSION: The incidence of in situ vulvar carcinoma is increasing. The incidence of invasive vulvar cancer is also increasing but at a much lower rate.

Original languageEnglish (US)
Pages (from-to)1018-1022
Number of pages5
JournalObstetrics and Gynecology
Volume107
Issue number5
DOIs
StatePublished - May 2006
Externally publishedYes

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Carcinoma in Situ
Vulvar Neoplasms
Incidence
Carcinoma
Neoplasms
Epidemiology
Age Groups
Demography
Databases

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Trends in the incidence of invasive and in situ vulvar carcinoma. / Judson, Patricia L.; Habermann, Elizabeth B; Baxter, Nancy N.; Durham, Sara B.; Virnig, Beth A.

In: Obstetrics and Gynecology, Vol. 107, No. 5, 05.2006, p. 1018-1022.

Research output: Contribution to journalArticle

Judson, Patricia L. ; Habermann, Elizabeth B ; Baxter, Nancy N. ; Durham, Sara B. ; Virnig, Beth A. / Trends in the incidence of invasive and in situ vulvar carcinoma. In: Obstetrics and Gynecology. 2006 ; Vol. 107, No. 5. pp. 1018-1022.
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N2 - OBJECTIVE: To characterize the incidence of vulvar carcinoma in situ and vulvar cancer over time. METHODS: We used the Surveillance Epidemiology and End Results database to assess trends in the incidence of vulvar cancer over a 28-year period (1973 through 2000) and determined whether there had been a change in incidence over time. Information collected included patient characteristics, primary tumor site, tumor grade, and follow-up for vital status. We calculated the incidence rates by decade of age, used χ2 tests to compare demographic characteristics, and tested for trends in incidence over time. RESULTS: A total of 13,176 in situ and invasive vulvar carcinomas were identified; 57% of the women were diagnosed with in situ, 44% with invasive disease. Vulvar carcinoma in situ increased 411% from 1973 to 2000. Invasive vulvar cancer increased 20% during the same period. The incidence rates for in situ and invasive vulvar carcinomas are distributed differently across the age groups. In situ carcinoma incidence increases until the age of 40-49 years and then decreases, whereas invasive vulvar cancer risk increases as a woman ages, increasing more quickly after 50 years of age. CONCLUSION: The incidence of in situ vulvar carcinoma is increasing. The incidence of invasive vulvar cancer is also increasing but at a much lower rate.

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