Trends in the association between age and in-hospital mortality after percutaneous coronary intervention national cardiovascular data registry experience

Mandeep Singh, Eric D. Peterson, Matthew T. Roe, Fang Shu Ou, John A. Spertus, John S. Rumsfeld, H. Vernon Anderson, Lloyd W. Klein, Kalon K.L. Ho, David R. Holmes

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

Background-Temporal trends and contemporary data characterizing the impact of patient age on in-hospital outcomes of percutaneous coronary interventions are lacking. We sought to determine the importance of age by assessing the in-hospital mortality of stratified age groups in the National Cardiovascular Data Registry. Methods and Results-In-hospital mortality after percutaneous coronary intervention on 1 410 069 patients was age stratified into 4 groups-group 1 (age <40, n=25 679), group 2 (40 to 59, n=496 204), group 3 (60 to 79, n=732 574), and group 4 (0, n=155 612)-admitted from January 1, 2001, to December 31, 2006. Overall in-hospital mortality was 1.22%; in-hospital mortality was 0.60%, 0.59%, 1.26%, and 3.16% in groups 1 to 4, respectively, P<0.0001. Overall temporal improvement per calendar year in the adjusted in-hospital mortality after percutaneous coronary intervention was noted in most groups; however, this finding was significant only in the 2 older age groups, group 3 (odds ratio, 0.94; 95% CI, 0.92 to 0.96) and group 4 (odds ratio, 0.95; 95% CI, 0.92 to 0.97). The absolute mortality reduction was greatest in the most elderly group, those over the age of 80 years. Conclusions-In-hospital mortality after percutaneous coronary intervention has fallen for all age groups over the past 6 years. However, the largest absolute reduction was seen among patients 80 years of age or older. (Circ Cardiovasc Intervent. 2009;2:20-26.)

Original languageEnglish (US)
Pages (from-to)20-26
Number of pages7
JournalCirculation: Cardiovascular Interventions
Volume2
Issue number1
DOIs
StatePublished - Feb 1 2009

Keywords

  • Age
  • Mortality
  • Percutaneous coronary interventions
  • Temporal trends

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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