Trends in Incidence, Characteristics, and In-Hospital Outcomes of Patients Presenting With Spontaneous Coronary Artery Dissection (From a National Population-Based Cohort Study Between 2004 and 2015)

Chayakrit Krittanawong, Anirudh Kumar, Hafeez Ul Hassan Virk, Bing Yue, Zhen Wang, Deepak L. Bhatt

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Though infrequent, spontaneous coronary artery dissection (SCAD) is increasingly recognized as an important cause of acute coronary syndrome (ACS), particularly in young healthy women. However, the population-based incidence of SCAD is unknown. We evaluated the incidence, patient characteristics, clinical characteristics, and mortality of SCAD-related hospitalizations using data from a national population-based cohort study from January 1, 2004, to September 30, 2015. In 13,573,200 patients who presented with an acute coronary syndrome, 66,360 (0.49%) of patients were diagnosed with SCAD. The mean age was 63.1 ± 13.2 years and 44.2% were women. In-hospital mortality of SCAD patients was 4.2%: 5.03% in females and 3.55% in males (p < 0.001). In conclusion, SCAD is an uncommon diagnosis that should be considered in males and older patients in addition to females presenting with ACS. Most SCAD patients today are managed medically. In-hospital mortality is comparable to that of other patients who present with ACS.

Original languageEnglish (US)
Pages (from-to)1617-1623
Number of pages7
JournalAmerican Journal of Cardiology
Volume122
Issue number10
DOIs
StatePublished - Nov 15 2018

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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