Trends in incidence and clinical presentation of temporal arteritis in olmsted county, minnesota, 1950–1985

E. B.V. Machado, Clement Michet, David J. Ballard, Gene G. Hunder, C. Mary Beard, Chu‐Pin ‐P Chu, W. Michael O'Fallon

Research output: Contribution to journalArticle

253 Citations (Scopus)

Abstract

Ninety‐four Olmsted County, Minnesota residents with temporal arteritis (TA) initially diagnosed between 1950 and 1985 (incidence cohort) were identified. The age‐ and sex‐adjusted incidence of TA per 100,000 population age 50 years or older was 17.0 (95% confidence interval [CI] 13.6–20.5), with a marked increase in incidence with age and a threefold greater incidence in women (23.4, 95% CI 18.2–28.7) than in men (7.4, 95% CI 3.7–11.0). The previously described secular increase in TA incidence in Olmsted County women continued from 1970 through 1985, while TA incidence in men declined in this latter time period. Although the frequency of classic clinical manifestations of TA declined over time, the percentage of patients undergoing biopsy who have positive specimens remained relatively constant (women 41%, men 26%). The incidence rate of temporal artery biopsy also increased for women during this period, but declined for men, suggesting that the differing trends in TA incidence by sex may be partially attributable to a detection bias. Future research in TA etiology and epidemiology should focus on possible causal factors linked to the differential TA incidence by sex.

Original languageEnglish (US)
Pages (from-to)745-749
Number of pages5
JournalArthritis & Rheumatism
Volume31
Issue number6
DOIs
StatePublished - Jan 1 1988

Fingerprint

Giant Cell Arteritis
Incidence
Confidence Intervals
Biopsy
Temporal Arteries
Epidemiology

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

Cite this

Machado, E. B. V., Michet, C., Ballard, D. J., Hunder, G. G., Beard, C. M., Chu, CP. P., & O'Fallon, W. M. (1988). Trends in incidence and clinical presentation of temporal arteritis in olmsted county, minnesota, 1950–1985. Arthritis & Rheumatism, 31(6), 745-749. https://doi.org/10.1002/art.1780310607

Trends in incidence and clinical presentation of temporal arteritis in olmsted county, minnesota, 1950–1985. / Machado, E. B.V.; Michet, Clement; Ballard, David J.; Hunder, Gene G.; Beard, C. Mary; Chu, Chu‐Pin ‐P; O'Fallon, W. Michael.

In: Arthritis & Rheumatism, Vol. 31, No. 6, 01.01.1988, p. 745-749.

Research output: Contribution to journalArticle

Machado, E. B.V. ; Michet, Clement ; Ballard, David J. ; Hunder, Gene G. ; Beard, C. Mary ; Chu, Chu‐Pin ‐P ; O'Fallon, W. Michael. / Trends in incidence and clinical presentation of temporal arteritis in olmsted county, minnesota, 1950–1985. In: Arthritis & Rheumatism. 1988 ; Vol. 31, No. 6. pp. 745-749.
@article{c616c1d296ae4577a6c184078fe38868,
title = "Trends in incidence and clinical presentation of temporal arteritis in olmsted county, minnesota, 1950–1985",
abstract = "Ninety‐four Olmsted County, Minnesota residents with temporal arteritis (TA) initially diagnosed between 1950 and 1985 (incidence cohort) were identified. The age‐ and sex‐adjusted incidence of TA per 100,000 population age 50 years or older was 17.0 (95{\%} confidence interval [CI] 13.6–20.5), with a marked increase in incidence with age and a threefold greater incidence in women (23.4, 95{\%} CI 18.2–28.7) than in men (7.4, 95{\%} CI 3.7–11.0). The previously described secular increase in TA incidence in Olmsted County women continued from 1970 through 1985, while TA incidence in men declined in this latter time period. Although the frequency of classic clinical manifestations of TA declined over time, the percentage of patients undergoing biopsy who have positive specimens remained relatively constant (women 41{\%}, men 26{\%}). The incidence rate of temporal artery biopsy also increased for women during this period, but declined for men, suggesting that the differing trends in TA incidence by sex may be partially attributable to a detection bias. Future research in TA etiology and epidemiology should focus on possible causal factors linked to the differential TA incidence by sex.",
author = "Machado, {E. B.V.} and Clement Michet and Ballard, {David J.} and Hunder, {Gene G.} and Beard, {C. Mary} and Chu, {Chu‐Pin ‐P} and O'Fallon, {W. Michael}",
year = "1988",
month = "1",
day = "1",
doi = "10.1002/art.1780310607",
language = "English (US)",
volume = "31",
pages = "745--749",
journal = "Arthritis and Rheumatology",
issn = "2326-5191",
publisher = "John Wiley and Sons Ltd",
number = "6",

}

TY - JOUR

T1 - Trends in incidence and clinical presentation of temporal arteritis in olmsted county, minnesota, 1950–1985

AU - Machado, E. B.V.

AU - Michet, Clement

AU - Ballard, David J.

AU - Hunder, Gene G.

AU - Beard, C. Mary

AU - Chu, Chu‐Pin ‐P

AU - O'Fallon, W. Michael

PY - 1988/1/1

Y1 - 1988/1/1

N2 - Ninety‐four Olmsted County, Minnesota residents with temporal arteritis (TA) initially diagnosed between 1950 and 1985 (incidence cohort) were identified. The age‐ and sex‐adjusted incidence of TA per 100,000 population age 50 years or older was 17.0 (95% confidence interval [CI] 13.6–20.5), with a marked increase in incidence with age and a threefold greater incidence in women (23.4, 95% CI 18.2–28.7) than in men (7.4, 95% CI 3.7–11.0). The previously described secular increase in TA incidence in Olmsted County women continued from 1970 through 1985, while TA incidence in men declined in this latter time period. Although the frequency of classic clinical manifestations of TA declined over time, the percentage of patients undergoing biopsy who have positive specimens remained relatively constant (women 41%, men 26%). The incidence rate of temporal artery biopsy also increased for women during this period, but declined for men, suggesting that the differing trends in TA incidence by sex may be partially attributable to a detection bias. Future research in TA etiology and epidemiology should focus on possible causal factors linked to the differential TA incidence by sex.

AB - Ninety‐four Olmsted County, Minnesota residents with temporal arteritis (TA) initially diagnosed between 1950 and 1985 (incidence cohort) were identified. The age‐ and sex‐adjusted incidence of TA per 100,000 population age 50 years or older was 17.0 (95% confidence interval [CI] 13.6–20.5), with a marked increase in incidence with age and a threefold greater incidence in women (23.4, 95% CI 18.2–28.7) than in men (7.4, 95% CI 3.7–11.0). The previously described secular increase in TA incidence in Olmsted County women continued from 1970 through 1985, while TA incidence in men declined in this latter time period. Although the frequency of classic clinical manifestations of TA declined over time, the percentage of patients undergoing biopsy who have positive specimens remained relatively constant (women 41%, men 26%). The incidence rate of temporal artery biopsy also increased for women during this period, but declined for men, suggesting that the differing trends in TA incidence by sex may be partially attributable to a detection bias. Future research in TA etiology and epidemiology should focus on possible causal factors linked to the differential TA incidence by sex.

UR - http://www.scopus.com/inward/record.url?scp=0023885995&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023885995&partnerID=8YFLogxK

U2 - 10.1002/art.1780310607

DO - 10.1002/art.1780310607

M3 - Article

C2 - 3382448

AN - SCOPUS:0023885995

VL - 31

SP - 745

EP - 749

JO - Arthritis and Rheumatology

JF - Arthritis and Rheumatology

SN - 2326-5191

IS - 6

ER -