Trend toward improved day 100 and two-year survival following stem cell transplantation for AL: A comparison before and after 2006

M. A. Gertz, M. Q. Lacy, A. Dispenzieri, S. Kumar, S. R. Hayman, F. Buadi, D. Dingli, N. Leung, W. J. Hogan

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We report 422 patients transplanted for light chain amyloidosis. Day-100 all-cause mortality has fallen from 12% prior to 1 January 2006 to 7% after 1 January 2006 (p = 0.09). Survival at 2 years has likewise improved from 78 to 82%. Serum troponin T and NT-proBNP were the only predictors of early mortality. Refined patient selection has improved the safety margin for patients undergoing high-dose therapy, and therapy-related mortality has been reduced by 40%.

Original languageEnglish (US)
Pages (from-to)137-138
Number of pages2
JournalAmyloid
Volume18
Issue numberSUPPL. 1
DOIs
StatePublished - Jun 1 2011

ASJC Scopus subject areas

  • Internal Medicine

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