Treatment-resistant meningitis leading to the diagnosis of currarino syndrome: A case report

Autumn S. Kiefer; Priyanka Gupta; Salman Kirmani; Kara Schwartz; Nancy Henry; Philip R. Fischer

doi:10.1097/INF.0b013e3181945875

Treatment-resistant meningitis leading to the diagnosis of currarino syndrome: A case report

Autumn S. Kiefer, Priyanka Gupta, Salman Kirmani, Kara Schwartz, Nancy Henry, Philip R. Fischer

Medical Genetics

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A 20-day-old female infant developed fever. Sepsis evaluation revealed cerebrospinal fluid (CSF) pleocytosis and a modestly decreased CSF glucose. After 48 hours of broad-spectrum antibiotics, the infant remained febrile. Repeat CSF analysis showed increased pleocytosis and a very low glucose value. Subsequently, a rectothecal fistula and sacral abnormalities were found, leading to the diagnosis of Currarino syndrome. Parameningeal foci should be considered in treatment-resistant meningitis.

Original language	English (US)
Pages (from-to)	547-549
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	28
Issue number	6
DOIs	https://doi.org/10.1097/INF.0b013e3181945875
State	Published - Jun 2009

Keywords

Currarino syndrome
Currarino triad
Fistula
Meningitis
Parameningeal focus

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

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10.1097/INF.0b013e3181945875

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abstract = "A 20-day-old female infant developed fever. Sepsis evaluation revealed cerebrospinal fluid (CSF) pleocytosis and a modestly decreased CSF glucose. After 48 hours of broad-spectrum antibiotics, the infant remained febrile. Repeat CSF analysis showed increased pleocytosis and a very low glucose value. Subsequently, a rectothecal fistula and sacral abnormalities were found, leading to the diagnosis of Currarino syndrome. Parameningeal foci should be considered in treatment-resistant meningitis.",

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AU - Kiefer, Autumn S.

AU - Gupta, Priyanka

AU - Kirmani, Salman

AU - Schwartz, Kara

AU - Henry, Nancy

AU - Fischer, Philip R.

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AB - A 20-day-old female infant developed fever. Sepsis evaluation revealed cerebrospinal fluid (CSF) pleocytosis and a modestly decreased CSF glucose. After 48 hours of broad-spectrum antibiotics, the infant remained febrile. Repeat CSF analysis showed increased pleocytosis and a very low glucose value. Subsequently, a rectothecal fistula and sacral abnormalities were found, leading to the diagnosis of Currarino syndrome. Parameningeal foci should be considered in treatment-resistant meningitis.

KW - Currarino syndrome

KW - Currarino triad

KW - Fistula

KW - Meningitis

KW - Parameningeal focus

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Treatment-resistant meningitis leading to the diagnosis of currarino syndrome: A case report

Abstract

Keywords

ASJC Scopus subject areas

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