Treatment of patients with toxic multinodular goiter

Dana Erickson, Hossein Gharib, Hongzhe Li, Jon A. Van Heerden

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The medical records of 253 patients evaluated for toxic multinodular goiter from 1975 through 1993 were reviewed to determine treatment trends, success, and complications. Of the 235 (93%) treated, 174 (74%) received surgical treatment and 61 (26%) received radioiodine (131I) treatment. Three months after initial treatment, 82% of surgically treated patients became euthyroid or hypothyroid compared with 21% of the 131I group. Among the 131I-treated patients, 20% required a second treatment, whereas none needed further treatment in the surgical group. At 2 years, the estimated probability of success was similar. The probability of post-treatment hypothyroidism was significantly higher for surgically treated patients, which is expected.

Original languageEnglish (US)
Pages (from-to)277-282
Number of pages6
JournalThyroid
Volume8
Issue number4
StatePublished - 1998

Fingerprint

Poisons
Goiter
Therapeutics
Hypothyroidism
Medical Records

ASJC Scopus subject areas

  • Endocrinology

Cite this

Erickson, D., Gharib, H., Li, H., & Van Heerden, J. A. (1998). Treatment of patients with toxic multinodular goiter. Thyroid, 8(4), 277-282.

Treatment of patients with toxic multinodular goiter. / Erickson, Dana; Gharib, Hossein; Li, Hongzhe; Van Heerden, Jon A.

In: Thyroid, Vol. 8, No. 4, 1998, p. 277-282.

Research output: Contribution to journalArticle

Erickson, D, Gharib, H, Li, H & Van Heerden, JA 1998, 'Treatment of patients with toxic multinodular goiter', Thyroid, vol. 8, no. 4, pp. 277-282.
Erickson D, Gharib H, Li H, Van Heerden JA. Treatment of patients with toxic multinodular goiter. Thyroid. 1998;8(4):277-282.
Erickson, Dana ; Gharib, Hossein ; Li, Hongzhe ; Van Heerden, Jon A. / Treatment of patients with toxic multinodular goiter. In: Thyroid. 1998 ; Vol. 8, No. 4. pp. 277-282.
@article{e0020df3ccdd4b0eaccbfe3ecc1ed150,
title = "Treatment of patients with toxic multinodular goiter",
abstract = "The medical records of 253 patients evaluated for toxic multinodular goiter from 1975 through 1993 were reviewed to determine treatment trends, success, and complications. Of the 235 (93{\%}) treated, 174 (74{\%}) received surgical treatment and 61 (26{\%}) received radioiodine (131I) treatment. Three months after initial treatment, 82{\%} of surgically treated patients became euthyroid or hypothyroid compared with 21{\%} of the 131I group. Among the 131I-treated patients, 20{\%} required a second treatment, whereas none needed further treatment in the surgical group. At 2 years, the estimated probability of success was similar. The probability of post-treatment hypothyroidism was significantly higher for surgically treated patients, which is expected.",
author = "Dana Erickson and Hossein Gharib and Hongzhe Li and {Van Heerden}, {Jon A.}",
year = "1998",
language = "English (US)",
volume = "8",
pages = "277--282",
journal = "Thyroid",
issn = "1050-7256",
publisher = "Mary Ann Liebert Inc.",
number = "4",

}

TY - JOUR

T1 - Treatment of patients with toxic multinodular goiter

AU - Erickson, Dana

AU - Gharib, Hossein

AU - Li, Hongzhe

AU - Van Heerden, Jon A.

PY - 1998

Y1 - 1998

N2 - The medical records of 253 patients evaluated for toxic multinodular goiter from 1975 through 1993 were reviewed to determine treatment trends, success, and complications. Of the 235 (93%) treated, 174 (74%) received surgical treatment and 61 (26%) received radioiodine (131I) treatment. Three months after initial treatment, 82% of surgically treated patients became euthyroid or hypothyroid compared with 21% of the 131I group. Among the 131I-treated patients, 20% required a second treatment, whereas none needed further treatment in the surgical group. At 2 years, the estimated probability of success was similar. The probability of post-treatment hypothyroidism was significantly higher for surgically treated patients, which is expected.

AB - The medical records of 253 patients evaluated for toxic multinodular goiter from 1975 through 1993 were reviewed to determine treatment trends, success, and complications. Of the 235 (93%) treated, 174 (74%) received surgical treatment and 61 (26%) received radioiodine (131I) treatment. Three months after initial treatment, 82% of surgically treated patients became euthyroid or hypothyroid compared with 21% of the 131I group. Among the 131I-treated patients, 20% required a second treatment, whereas none needed further treatment in the surgical group. At 2 years, the estimated probability of success was similar. The probability of post-treatment hypothyroidism was significantly higher for surgically treated patients, which is expected.

UR - http://www.scopus.com/inward/record.url?scp=0031971485&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031971485&partnerID=8YFLogxK

M3 - Article

C2 - 9588491

AN - SCOPUS:0031971485

VL - 8

SP - 277

EP - 282

JO - Thyroid

JF - Thyroid

SN - 1050-7256

IS - 4

ER -