Treatment of dementia with lewy bodies

Brendon P. Boot, Eric M. McDade, Scott M. McGinnis, Bradley F. Boeve

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Dementia with Lewy bodies (DLB) is a multisystem disorder with diverse disease expression. A treatment regime restricted to the cognitive aspects of the disease does no favor to patients. Instead, patients should be educated to recognize the symptoms of this multisystem involvement. There are no treatments that slow the progression of disease, but symptomatic treatments can be effective. When thinking about treatment, we find it useful to divide the symptoms and signs into five categories: (a) cognitive features, (b) neuropsychiatric features, (c) motor dysfunction, (d) autonomic dysfunction, and (e) sleep dysfunction. Clinicians, funding bodies and industry are increasingly recognizing the importance of this common and debilitating disease.

Original languageEnglish (US)
Pages (from-to)738-764
Number of pages27
JournalCurrent Treatment Options in Neurology
Volume15
Issue number6
DOIs
StatePublished - Dec 2013

Keywords

  • Antipsychotic
  • Cholinesterase inhibitors
  • Dementia with Lewy bodies
  • Dysautonomia
  • Parkinson's disease dementia
  • REM sleep behavior disorder
  • Treatment

ASJC Scopus subject areas

  • Clinical Neurology

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