Treatment of colorectal cancer in older patients

International Society of Geriatric Oncology (SIOG) consensus recommendations 2013

Demetris Papamichael, R. A. Audisio, B. Glimelius, A. de Gramont, R. Glynne-Jones, D. Haller, C. H. Köhne, S. Rostoft, V. Lemmens, E. Mitry, H. Rutten, D. Sargent, J. Sastre, M. Seymour, N. Starling, E. van Cutsem, M. Aapro

Research output: Contribution to journalArticle

109 Citations (Scopus)

Abstract

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers in Europe and worldwide, with the peak incidence in patients > 70 years of age. However, as the treatment algorithms for the treatment of patients with CRC become ever more complex, it is clear that a significant percentage of older CRC patients (>70 years) are being less than optimally treated. This document provides a summary of an International Society of Geriatric Oncology (SIOG) task force meeting convened in Paris in 2013 to update the existing expert recommendations for the treatment of older (geriatric) CRC patients published in 2009 and includes overviews of the recent data on epidemiology, geriatric assessment as it relates to surgery and oncology, and the ability of older CRC patients to tolerate surgery, adjuvant chemotherapy, treatment of their metastatic disease including palliative chemotherapy with and without the use of the biologics, and finally the use of adjuvant and palliative radiotherapy in the treatment of older rectal cancer patients. An overview of each area was presented by one of the task force experts and comments invited from other task force members.

Original languageEnglish (US)
Pages (from-to)463-476
Number of pages14
JournalAnnals of Oncology
Volume26
Issue number3
DOIs
StatePublished - 2015

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Colorectal Neoplasms
Advisory Committees
Therapeutics
Geriatric Assessment
Adjuvant Radiotherapy
Paris
Adjuvant Chemotherapy
Rectal Neoplasms
Biological Products
Geriatrics
Epidemiology
Drug Therapy
Incidence
Neoplasms

Keywords

  • Colorectal cancer
  • Geriatric assessment
  • Guidelines
  • International society of geriatric oncology
  • Older
  • SIOG

ASJC Scopus subject areas

  • Oncology
  • Hematology

Cite this

Papamichael, D., Audisio, R. A., Glimelius, B., de Gramont, A., Glynne-Jones, R., Haller, D., ... Aapro, M. (2015). Treatment of colorectal cancer in older patients: International Society of Geriatric Oncology (SIOG) consensus recommendations 2013. Annals of Oncology, 26(3), 463-476. https://doi.org/10.1093/annonc/mdu253

Treatment of colorectal cancer in older patients : International Society of Geriatric Oncology (SIOG) consensus recommendations 2013. / Papamichael, Demetris; Audisio, R. A.; Glimelius, B.; de Gramont, A.; Glynne-Jones, R.; Haller, D.; Köhne, C. H.; Rostoft, S.; Lemmens, V.; Mitry, E.; Rutten, H.; Sargent, D.; Sastre, J.; Seymour, M.; Starling, N.; van Cutsem, E.; Aapro, M.

In: Annals of Oncology, Vol. 26, No. 3, 2015, p. 463-476.

Research output: Contribution to journalArticle

Papamichael, D, Audisio, RA, Glimelius, B, de Gramont, A, Glynne-Jones, R, Haller, D, Köhne, CH, Rostoft, S, Lemmens, V, Mitry, E, Rutten, H, Sargent, D, Sastre, J, Seymour, M, Starling, N, van Cutsem, E & Aapro, M 2015, 'Treatment of colorectal cancer in older patients: International Society of Geriatric Oncology (SIOG) consensus recommendations 2013', Annals of Oncology, vol. 26, no. 3, pp. 463-476. https://doi.org/10.1093/annonc/mdu253
Papamichael, Demetris ; Audisio, R. A. ; Glimelius, B. ; de Gramont, A. ; Glynne-Jones, R. ; Haller, D. ; Köhne, C. H. ; Rostoft, S. ; Lemmens, V. ; Mitry, E. ; Rutten, H. ; Sargent, D. ; Sastre, J. ; Seymour, M. ; Starling, N. ; van Cutsem, E. ; Aapro, M. / Treatment of colorectal cancer in older patients : International Society of Geriatric Oncology (SIOG) consensus recommendations 2013. In: Annals of Oncology. 2015 ; Vol. 26, No. 3. pp. 463-476.
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