RTX is the first proven alternative to CYC for remission induction in severe GPA and MPA. RTX is the preferred agent for patients presenting with severe disease flares, and its use had become the de facto standard of care for patients with chronically relapsing refractory GPA. Its use in EGPA requires further investigation.
- Antineutrophil cytoplasmic antibody
- Antineutrophil cytoplasmic antibody associated vasculitis
- Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)
- Granulomatosis with polyangiitis (Wegener's granulomatosis)
- Microscopic polyangiitis
ASJC Scopus subject areas