Treating complex nervous system vascular disorders through a "needle stick": Origins, evolution, and future of neuroendovascular therapy

L. Nelson Hopkins, Giuseppe Lanzino, Lee R. Guterman

Research output: Contribution to journalReview article

41 Scopus citations


IN THE PAST few decades, dramatic improvements have occurred in the field of neuroendovascular surgery. Endovascular therapy today is a well-established treatment modality for a variety of cerebrovascular and nonvascular central nervous system diseases. The foundation of this spectacular evolution was laid by the efforts of pioneering visionaries who often worked alone and under difficult, almost impossible, conditions. Ongoing device development and refinement have revolutionized the field at a dizzying, exhilarating pace. With a better understanding of the molecular basis of diseases and further advancements in gene therapy, neuroendovascular techniques have an enormous potential for application to the entire spectrum of central nervous system diseases as a minimally invasive vehicle for the delivery of biological factors.

Original languageEnglish (US)
Pages (from-to)463-475
Number of pages13
Issue number3
StatePublished - 2001
Externally publishedYes



  • Arteriovenous malformations
  • Carotid stenosis
  • Endovascular therapy
  • Intracranial aneurysms
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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